Gold nanoparticle based signal enhancement liquid crystal biosensors for DNA hybridization assays

被引：67

作者：

Yang, Shengyuan ^{[1
,2
]}

Liu, Yanmei ^{[1
]}

Tan, Hui ^{[1
]}

Wu, Chao ^{[1
]}

Wu, Zhaoyang ^{[1
]}

Shen, Guoli ^{[1
]}

Yu, Ruqin ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

[2] Univ S China, Coll Publ Hlth, Hengyang 421001, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 23期

基金：

中国国家自然科学基金;

关键词：

BOVINE SERUM-ALBUMIN; SOLID-SURFACES; AMPLIFICATION; TRANSITIONS; PROTEINS; PROBES; FILMS; QUANTIFICATION; ORIENTATIONS; ELECTRODES;

D O I：

10.1039/c2cc17861c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel signal enhanced liquid crystal biosensor based on using AuNPs for highly sensitive DNA detection has been developed. This biosensor not only significantly decreases the detection limit, but also offers a simple detection process and shows a good selectivity to distinguish perfectly matched target DNA from two-base mismatched DNA.

引用

页码：2861 / 2863

页数：3

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