Natural Nitrogenous Sesquiterpenoids and Their Bioactivity: A Review

被引：24
作者：
Chen, De-Li [1 ,2 ]
Wang, Bo-Wen [3 ]
Sun, Zhao-Cui [1 ]
Yang, Jun-Shan [1 ]
Xu, Xu-Dong [1 ]
Ma, Guo-Xu [1 ,2 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Plant Dev, 151 Malianwa North Rd, Beijing 100193, Peoples R China
[2] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Plant Dev, Hainan Prov Key Lab Resources Conservat & Dev Sou, Hainan Branch, Haikou 570311, Hainan, Peoples R China
[3] Hainan Univ, Sch Chem Engn & Technol, Haikou 570228, Hainan, Peoples R China
来源：
MOLECULES | 2020年 / 25卷 / 11期
基金：
海南省自然科学基金; 中国国家自然科学基金;
关键词：
nitrogenous sesquiterpenoids; celastraceae; marine sponge; fungi; bioactivities; MARINE SPONGE; NITROBENZOYL SESQUITERPENOIDS; CHEMICAL-CONSTITUENTS; PYRIDINE ALKALOIDS; DERIVATIVES; PRODUCTS; LEAVES; ROOTS; AMINOQUINONES; ENDOPHYTE;
D O I：
10.3390/molecules25112485
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Nitrogenous sesquiterpenoids fromnatural sourcesare rare, so unsurprisingly neither the potentially valuable bioactivity nor thebroad structural diversity of nitrogenous sesquiterpenoids has been reviewed before. This report covers the progressduring the decade from 2010 to February 2020 on the isolation, identification, and bioactivity of 391 nitrogen-containing natural sesquiterpenes from terrestrial plant, marine organisms, and microorganisms. This complete and in-depth reviewshouldbe helpful for discovering and developing new drugs of medicinal valuerelated to natural nitrogenous sesquiterpenoids.
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页数：32
相关论文
共 95 条
[1]   A dimeric urea of the bisabolene sesquiterpene from the Okinawan marine sponge Axinyssa sp inhibits protein tyrosine phosphatase 1B activity in Huh-7 human hepatoma cells [J].
Abdjul, Delfly B. ;
Kanno, Syu-ichi ;
Yamazaki, Hiroyuki ;
Ukai, Kazuyo ;
Namikoshi, Michio .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (02) :315-317
[2]   Alcyonacea: A Potential Source for Production of Nitrogen-Containing Metabolites [J].
Alarif, Walied Mohamed ;
Abdel-Lateff, Ahmed ;
Alorfi, Hajer Saeed ;
Alburae, Najla Ali .
MOLECULES, 2019, 24 (02)
[3]   A New Sesquiterpenoid Aminoquinone from an Indonesian Marine Sponge [J].
Balansa, Walter ;
Mettal, Ute ;
Wuisan, Zerlina G. ;
Plubrukarn, Anuchit ;
Ijong, Frans G. ;
Liu, Yang ;
Schaeberle, Till F. .
MARINE DRUGS, 2019, 17 (03)
[4]   Bioactive natural products in cancer prevention and therapy: Progress and promise [J].
Bishayee, Anupam ;
Sethi, Gautam .
SEMINARS IN CANCER BIOLOGY, 2016, 40-41 :1-3
[5]   Natural Products Containing a Nitrogen-Nitrogen Bond [J].
Blair, Lachlan M. ;
Sperry, Jonathan .
JOURNAL OF NATURAL PRODUCTS, 2013, 76 (04) :794-812
[6]   Spiroalanpyrroids A and B, sesquiterpene alkaloids with a unique spiro-eudesmanolide-pyrrolizidine skeleton from Inula helenium [J].
Cai, You-Sheng ;
Wu, Zi ;
Zheng, Xiao-Qin ;
Wang, Cong ;
Wang, Jian-Rong ;
Zhang, Xin-Xin ;
Qiu, Guofu ;
Zhu, Kongkai ;
Cao, Shugeng ;
Yu, Jianqing .
ORGANIC CHEMISTRY FRONTIERS, 2020, 7 (02) :303-309
[7]   Sesquiterpenoids Lactones: Benefits to Plants and People [J].
Chadwick, Martin ;
Trewin, Harriet ;
Gawthrop, Frances ;
Wagstaff, Carol .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (06) :12780-12805
[8]   Two new sesquiterpene pyridine alkaloids from root barks of Celastrus angulatus [J].
Chang, Xia ;
Wang, Zhi-Yao ;
Chen, Xin ;
Ma, Yan-Ni ;
Zhang, Hai-Yan ;
Zhao, Tian-Zeng .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 21 (11) :1043-1051
[9]   Hybrid Isoprenoids from a Reeds Rhizosphere Soil Derived Actinomycete Streptomyces sp CHQ-64 [J].
Che, Qian ;
Zhu, Tianjiao ;
Qi, Xin ;
Mandi, Attila ;
Kurtan, Tibor ;
Mo, Xiaomei ;
Li, Jing ;
Gu, Qianqun ;
Li, Dehai .
ORGANIC LETTERS, 2012, 14 (13) :3438-3441
[10]   Sesquiterpenoids isolated from an endophyte fungus Diaporthe sp. [J].
Chen, Chao-Jun ;
Liu, Xian-Xian ;
Zhang, Wen-Jing ;
Zang, Le-Yun ;
Wang, Gang ;
Ng, Seik Weng ;
Tan, Ren-Xiang ;
Ge, Hui-Ming .
RSC ADVANCES, 2015, 5 (23) :17559-17565
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