Intraoperative irradiation: precision medicine for quality cancer control promotion

被引：26
作者：
Calvo, Felipe A. [1 ,2 ,3 ]
机构：
[1] Univ Complutense Madrid, Hosp Gen Univ Gregorio Maranon, Dept Radiat Oncol, Dept Oncol, Madrid, Spain
[2] Inst Invest Sanitaria Gregorio Maranon, Grp Oncol Interdisciplinar & Biotecnol, Proyecto PI15 02121, Madrid, Spain
[3] Gobierno Espana, Inst Salud Carlos III, Minist Econ Competitividad, Madrid, Spain
来源：
RADIATION ONCOLOGY | 2017年 / 12卷
关键词：
Intraoperative irradiation; Precision medicine; Real-time surgical exploration; High single dose radiotherapy; BEAM RADIATION-THERAPY; MULTICENTRIC POOLED ANALYSIS; ELECTRON RADIOTHERAPY; EXTERNAL-BEAM; SURGICAL RESECTION; RECTAL-CANCER; RECURRENT; SURGERY; BOOST; FEASIBILITY;
D O I：
10.1186/s13014-017-0764-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Intraoperative irradiation was implemented 4 decades ago, pioneering the efforts to improve precision in local cancer therapy by combining real-time surgical exploration/resection with high single dose radiotherapy (Gunderson et al., Intraoperative irradiation: techniques and results, 2011). Clinical and technical developments have led to very precise radiation dose deposit. The ability to deliver a very precise dose of radiation is an essential element of contemporary multidisciplinary individualized oncology. This issue of Radiation Oncology contains a collection of expert review articles and updates with relevant data regarding intraoperative radiotherapy. Technology, physics, biology of single dose and clinical results in a variety of cancer sites and histologies are described and analyzed. The state of the art for advanced cancer care through medical innovation opens a significant opportunity for individualize cancer management across a broad spectrum of clinical practice. The advantage for tailoring diagnostic and treatment decisions in an individualized fashion will translate into precise medical treatment.
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页数：5
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