Syntheses, characterization and DNA-binding studies of novel asymmetric tridentate polypyridine ligands and their heteroleptic ruthenium(II) complexes

被引：0

作者：

Jiang, CW ^{[1
]}

机构：

[1] Guangxi Univ Tradit Chinese Med, Sch Pharm, Nanning 530001, Peoples R China

来源：

ACTA CHIMICA SINICA | 2004年 / 62卷 / 07期

关键词：

ruthenium(II) complex; tridentate polypyridine ligand; DNA binding;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two novel asymmetric tridentate polypyridine ligands with as-triazole, 3-(1,10-phenanthrolin-2-yl)-1, 2, 4-triazole (PHT) and 3-(1, 10-phenanthrolin-2-yl)-5-methyl-1, 2, 4-triazole (PHMT) have been designed, synthesized, and characterized by microanalyses, FAB-MS, NMR, FT-IR, and W-vis. Their heteroleptic complexes [Ru (tpy) (PHMT)] (ClO4)(2) (.) H2O (Ru1) and [RU (tpy) (PHMT)] (ClO4)(2) (.) 2H(2)O (Ru2) were synthesized and investigated with microanalyses, ES-MS, NMR and cyclic voltammetry. DNA binding mechanisms of the complexes were studied by electronic absorption spectra, competitive binding, and viscosity measurements. The results indicated that the modes of these two complexes interacting with DNA were electrostatic interaction, and the DNA-binding of Rut was stronger than that of Ru1.

引用

页码：692 / 696

页数：5

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