Don't leave home without it: the IL-23 visa to TH-17 cells

被引:11
作者
Chung, Yeonseok [1 ]
Dong, Chen [1 ]
机构
[1] Univ Texas Houston, MD Anderson Canc Ctr, Dept Immunol, Houston, TX 77030 USA
关键词
T-CELLS; INFLAMMATION; CYTOKINE; PATHOLOGY; DRIVE;
D O I
10.1038/ni0309-236
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Interleukin 23 is tightly associated with T-H-17 cell-mediated inflammation and autoimmunity. A new study of mice deficient in its receptor shows that interleukin 23 is required for the terminal differentiation of T-H-17 cells in vivo.
引用
收藏
页码:236 / 238
页数:3
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