Carotid Artery Stenting in Patients With Acute Coronary Syndrome: A Possible Primary Therapy for Symptomatic Carotid Stenosis

被引:1
|
作者
Casana, Renato [1 ]
Halliday, Alison [6 ]
Bianchi, Paolo [1 ]
Fresa, Emanuele [2 ]
Silani, Vincenzo [3 ,7 ]
Parati, Gianfranco [4 ,8 ]
Blengino, Simonetta [4 ]
Cireni, Lea [4 ]
Adobbati, Laura [3 ]
Calvillo, Laura [5 ]
Tolva, Valerio S. [1 ,8 ]
机构
[1] Ist Auxol Italiano IRCCS, Dept Surg, Milan, Italy
[2] Ist Auxol Italiano IRCCS, Dept Biomed Engn, Milan, Italy
[3] Ist Auxol Italiano IRCCS, Dept Neurol Stroke Unit, Milan, Italy
[4] Ist Auxol Italiano IRCCS, S Luca Hosp, Dept Cardiovasc Neural & Metab Sci, Milan, Italy
[5] Ist Auxol Italiano IRCCS, Lab Cardiovasc Genet, Milan, Italy
[6] Univ Oxford, Dept Surg, Oxford OX1 2JD, England
[7] Univ Milan, Dino Ferrari Ctr, Dept Pathophysiol & Transplantat, Milan, Italy
[8] Univ Milano Bicocca, Milan, Italy
关键词
carotid artery stenting; carotid stenosis; stroke; coronary angioplasty; coronary artery disease; percutaneous coronary intervention; cerebral protection; myocardial infarction; LONG-TERM OUTCOMES; HIGH-RISK; ENDARTERECTOMY; STROKE; INTERVENTION; REGISTRY; SURGERY;
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). Methods: Between January 2009 and July 2011, 28 consecutive patients (18 women; mean age 66 years, range 42-82) underwent protected CAS for symptomatic carotid stenosis following recent PTCA that included bare or drug-eluting stents requiring uninterrupted dual antiplatelet therapy. Primary technical success, neurological complications, major adverse cardiovascular events, and death were evaluated at 30 days and over midterm follow-up. Results: Technical success was 96%; 1 patient suffered a nonfatal major stroke (3.5% 30-day stroke rate) during the procedure. During a median 21.6-month follow-up, 4 (14%) patients died of myocardial infarction (all diabetic smokers with ejection fractions <40%), but there were no new neurological events. Estimated survival was 89.3% at 2 years. Further coronary interventions were performed in 2 diabetic patients with a body mass index >34 kg/m(2). Conclusion: This preliminary experience demonstrated that CAS is a reasonable, safe, and effective treatment for patients with symptomatic carotid artery stenosis who were recently treated with coronary stents requiring uninterrupted dual antiplatelet therapy.
引用
收藏
页码:546 / 551
页数:6
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