Early versus Conventional Treatment for Patent Ductus Arteriosus in Preterm Infants

被引：3

作者：

Candel-Pau, Julla ^{[1
,2
]}

Linde Sillo, Angeles ^{[2
]}

Castillo Salinas, Felix ^{[2
]}

Coma Redon, Ermengol ^{[3
]}

Ferrer Menduina, Queralt ^{[4
]}

Albert, Dimpna C. ^{[4
]}

机构：

[1] Vail dHebron Res Inst, Neonatol Unit, Barcelona 08035, Spain

[2] Hosp Univ Vail dHebron, Neonatol Unit, Barcelona, Spain

[3] Hosp Univ Vail dHebron, Dept Epidemiol & Prevent Med, Barcelona, Spain

[4] Hosp Univ Vail dHebron, Dept Pediat Cardiol, Barcelona, Spain

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 2013年 / 30卷 / 04期

关键词：

patent ductus arteriosus; indomethacin; early treatment; preterm; BIRTH-WEIGHT INFANTS; SPONTANEOUS INTESTINAL PERFORATION; RESPIRATORY-DISTRESS-SYNDROME; PREMATURE-INFANTS; BRONCHOPULMONARY DYSPLASIA; NECROTIZING ENTEROCOLITIS; INDOMETHACIN PROPHYLAXIS; RISK-FACTORS; DEXAMETHASONE TREATMENT; MANAGEMENT;

D O I：

10.1055/s-0032-1324696

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective After the introduction of a new protocol based on the early treatment with indomethacin for patent ductus arteriosus, the objective of this study was to assess the safety and efficacy of this new practice in comparison with the safety and efficacy of the conventional treatment in a high-risk population. Study Design We conducted a retrospective cohort study including 154 newborns with an average gestational age of 26.4 weeks (1.37 standard deviation) and an average birth weight of 855 g (201.5 standard deviation). A statistically descriptive analysis was performed with SPSS Statistics Pack version 17.0. Results and Conclusions We did not find any statistically significant differences in the clinical features of the two treatment groups, nor in the main efficacy, morbidity, and mortality results.

引用

页码：289 / 295

页数：7

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