COMPARING THE CLINICAL AND RADIOGRAPHIC OUTCOMES OF PULPOTOMIES IN PRIMARY MOLARS USING BIOACTIVE ENDODONTIC MATERIALS AND FERRIC SULFATE -A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS''

被引:1
作者
Gopinath, Vellore kannan [1 ]
Pulikkotil, Shaju Jacob [2 ]
Veettil, Sajesh K. [3 ]
Dharmarajan, Lalli [4 ]
Prakash, Ponnudurai Samuel gnana [4 ]
Dhar, Vineet [5 ]
Jayaraman, Jayakumar [6 ]
机构
[1] Univ Sharjah, Coll Dent Med, Dept Prevent & Restorat Dent, Sharjah, U Arab Emirates
[2] Int Med Univ, Sch Dent, Div Clin Dent, Kuala Lumpur, Malaysia
[3] Univ Utah, Coll Pharm, Dept Pharmacotherapy, Salt Lake City, UT USA
[4] S R M Dent Coll & Hosp, Dept Periodont, Chennai, India
[5] Univ Maryland, Sch Dent, Dept Orthodont & Pediat Dent, Baltimore, MD USA
[6] Virginia Commonwealth Univ, Sch Dent, Dept Pediat Dent, Richmond, VA USA
关键词
Ferric Sulphate; Bioactive endodontic materials; systematic review; randomized clinical trials; meta-analysis; MINERAL TRIOXIDE AGGREGATE; VITAL PULP THERAPY; IN-VITRO TOXICITY; PRIMARY TEETH; SUCCESS RATES; DEEP CARIES; PART I; FORMOCRESOL; MTA;
D O I
10.1016/j.jebdp.2022.101770
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objective To compare the clinical and radiographic outcomes of pulpotomies in primary molars using bioactive endodontic materials and ferric sulfate. Design The search was conducted in PubMed, Ebscohost, ProQuest, and Scopus databases till June 2021. Children undergoing pulpotomy therapy in primary molars treated with ferric sulfate (FS) and bioactive endodontic materials were evaluated for clinical and radiographic success. Meta-analysis was performed on a random-effects model to assess the success at 6,12,18, and 24 months. The quality of studies was evaluated using the Cochrane risk of bias tool for randomized trials Results No significant difference was observed between Mineral trioxide aggregate (MTA) and FS at 24 months for both clinical [RR0.98 (95%CI 0.15,6.34), I-2 = 0%] and radiographic [RR0.74 (95%CI: 0.23,2.43), I-2 = 0%] success. At 6 months [RR1.36 (95%CI: 0.10,19.34), I-2 = 33%], no difference was observed in the clinical [RR1.00 (95%CI: 0.95,1.05), I-2 = 0%] and radiographic success [RR0.99 (95%CI: 0.88,1.11), I-2 = 51%] between Biodentine (BD), FS and radiographic success of calcium enriched cement and FS [RR0.25 (95%CI: 0.03, 2.22), I-2 = 0%]. Conclusion Amongst bioactive materials, MTA and FS demonstrated equal success rates in both clinical and radiographic outcomes with follow-up periods of up to 24 months. Future, high-quality trials are required to verify the result of the current review.
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页数:13
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