o-lodoxybenzoic Acid Mediated Oxidative Desulfurization Initiated Domino Reactions for Synthesis of Azoles

被引：92

作者：

Chaudhari, Pramod S. ^{[1
]}

Pathare, Sagar P. ^{[1
]}

Akamanchi, Krishnacharaya G. ^{[1
]}

机构：

[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Mumbai 400019, Maharashtra, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 08期

关键词：

IODOXYBENZOIC ACID; DERIVATIVES; INHIBITORS; IBX;

D O I：

10.1021/jo2025509

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A systematic exploration of thiophilic ability of o-iodoxybenzoic acid (IBX) for oxidative desulfurization to trigger domino reactions leading to new methodologies for synthesis of different azoles is described. A variety of highly substituted oxadiazoles, thiadiazoles, triazoles, and tetrazoles have been successfully synthesized in good to excellent yields, starting from readily accessible thiosemicarbazides, bis-diarylthiourea, 1,3-disubtituted thiourea, and thioamides.

引用

页码：3716 / 3723

页数：8

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