A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

被引：102

作者：

Spears, KJ ^{[1
]}

Roe, AJ ^{[1
]}

Gally, DL ^{[1
]}

机构：

[1] Univ Edinburgh, Ctr Infect Dis, Zooton & Anim Pathogens Res Lab, Edinburgh EH16 4SB, Midlothian, Scotland

来源：

FEMS MICROBIOLOGY LETTERS | 2006年 / 255卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

enteropathogenic Escherichia coli; enterohaemorrhagic Escherichia coli; Shiga toxin; type III secretion;

D O I：

10.1111/j.1574-6968.2006.00119.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.

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收藏

页码：187 / 202

页数：16

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