Visceral leishmaniasis complicating a connective tissue disease: three case reports from Italy

被引:12
作者
Castellino, G
Govoni, M
Lo Monaco, A
Montecucco, C
Colombo, F
Trotta, F
机构
[1] Univ Ferrara, Cattedra Reumatol, I-44100 Ferrara, Italy
[2] Univ Ferrara, Unita Operat Reumatol, I-44100 Ferrara, Italy
[3] Policlin San Matteo, Cattedra Reumatol, I-27100 Pavia, Italy
[4] Policlin San Matteo, Unita Operat Reumatol, I-27100 Pavia, Italy
[5] Azienda Osped Osped Niguarda Ca Granda, Div Reuamtol, Milan, Italy
关键词
connective tissue diseases; immunosuppressive therapy; Leishmania donovani; pancytopenia; splenomegaly;
D O I
10.1191/0961203304lu518oa
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report the occurrence of visceral leishmaniasis in three patients coming from the northern part of Italy treated with immunosuppressive drugs for different rheumatic conditions. This paper highlights the importance of adequate work-up in those patients presenting with serious clinical manifestations that can complicate, exacerbate or mimic a systemic connective tissue disorder. A prompt diagnosis is very important because visceral leishmaniasis has a high mortality and, if untreated, can be fatal.
引用
收藏
页码:201 / 203
页数:3
相关论文
共 12 条
[1]  
BADARO R, 1986, LANCET, V1, P647
[2]   VISCERAL LEISHMANIASIS MIMICKING A FLARE OF SYSTEMIC LUPUS-ERYTHEMATOSUS [J].
BRAUN, J ;
SIEPER, J ;
SCHULTE, KL ;
THIEL, E ;
JANITSCHKE, K .
CLINICAL RHEUMATOLOGY, 1991, 10 (04) :445-448
[3]  
BROECKAERTVANORSHOVEN A, 1979, LANCET, V2, P740
[4]   VISCERAL LEISHMANIASIS IN IMMUNOCOMPROMISED HOSTS [J].
FERNANDEZGUERRERO, ML ;
AGUADO, JM ;
BUZON, L ;
BARROS, C ;
MONTALBAN, C ;
MARTIN, T ;
BOUZA, E .
AMERICAN JOURNAL OF MEDICINE, 1987, 83 (06) :1098-1102
[5]   Leishmaniasis mimicking collagen disease [J].
Galanakis, E ;
Siamopoulou, A ;
Lapatsanis, PD .
LANCET, 1997, 350 (9074) :368-369
[6]   One patient, two unusual conditions and three basic lessons [J].
GardnerMedwin, JMM ;
Powell, RJ .
ANNALS OF THE RHEUMATIC DISEASES, 1996, 55 (06) :350-352
[7]   Crossing of antinuclear antibodies and anti-leishmania antibodies [J].
Granel, B ;
Serratrice, J ;
Swiader, L ;
Gambarelli, F ;
Daniel, L ;
Fossat, C ;
Hesse-Bonerandi, S ;
Pache, X ;
Disdier, P ;
Weiller, PJ .
LUPUS, 2000, 9 (07) :548-550
[8]   FATAL INFECTIONS IN SYSTEMIC LUPUS-ERYTHEMATOSUS - THE ROLE OF OPPORTUNISTIC ORGANISMS [J].
HELLMANN, DB ;
PETRI, M ;
WHITINGOKEEFE, Q .
MEDICINE, 1987, 66 (05) :341-348
[9]   Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [J].
Hochberg, MC .
ARTHRITIS AND RHEUMATISM, 1997, 40 (09) :1725-1725
[10]   KILLING OF INTRACELLULAR LEISHMANIA-DONOVANI BY LYMPHOKINE-STIMULATED HUMAN MONONUCLEAR PHAGOCYTES - EVIDENCE THAT INTERFERON-GAMMA IS THE ACTIVATING LYMPHOKINE [J].
MURRAY, HW ;
RUBIN, BY ;
ROTHERMEL, CD .
JOURNAL OF CLINICAL INVESTIGATION, 1983, 72 (04) :1506-1510