Pediatric transplantation in Europe during the COVID-19 pandemic: Early impact on activity and healthcare

被引：33

作者：

Dona, Daniele ^{[1
]}

Torres Canizales, Juan ^{[2
]}

Benetti, Elisa ^{[3
]}

Cananzi, Mara ^{[4
]}

De Corti, Federica ^{[5
]}

Calore, Elisabetta ^{[6
]}

Hierro, Loreto ^{[2
,7
]}

Ramos Boluda, Esther ^{[8
]}

Melgosa Hijosa, Marta ^{[9
]}

Garcia Guereta, Luis ^{[10
]}

Perez Martinez, Antonio ^{[2
,11
]}

Barrios, Maribel ^{[12
]}

Costa Reis, Patricia ^{[13
]}

Teixeira, Ana ^{[14
]}

Lopes, Maria Francelina ^{[15
]}

Kalicinski, Piotr ^{[16
]}

Branchereau, Sophie ^{[17
]}

Boyer, Olivia ^{[18
]}

Debray, Dominque ^{[19
]}

Sciveres, Marco ^{[20
]}

Wennberg, Lars ^{[21
]}

Fischler, Bjorn ^{[22
]}

Barany, Peter ^{[23
]}

Baker, Alastair ^{[24
]}

Baumann, Ulrich ^{[25
]}

Schwerk, Nicolaus ^{[26
]}

Nicastro, Emanuele ^{[27
]}

Candusso, Manila ^{[28
]}

Toporski, Jacek ^{[29
]}

Sokal, Etienne ^{[30
]}

Stephenne, Xavier ^{[31
]}

Lindemans, Caroline ^{[32
]}

Miglinas, Marius ^{[33
]}

Rascon, Jelena ^{[34
]}

Jara, Paloma ^{[2
,7
]}

机构：

[1] Univ Hosp Padova, Dept Womens & Childrens Hlth, Pediat Infect Dis, Padua, Italy

[2] La Paz Univ Hosp, La Paz Inst Biomed Res IdiPAZ, Madrid, Spain

[3] Univ Hosp Padova, Dept Womens & Childrens Hlth, Pediat Nephrol Dialysis & Transplant Unit, Padua, Italy

[4] Univ Hosp Padova, Dept Womens & Childrens Hlth, Pediat Gastroenterol Digest Endoscopy Hepatol & C, Padua, Italy

[5] Univ Hosp Padova, Dept Womens & Childrens Hlth, Pediat Surg, Padua, Italy

[6] Univ Hosp Padova, Dept Womens & Childrens Hlth, Pediat Hematol Oncol & Stem Cell Transplant Div, Padua, Italy

[7] La Paz Univ Hosp, Pediat Hepatol Dept, Madrid, Spain

[8] La Paz Univ Hosp, Pediat Gastroenterol Intestinal Rehabil Unit, Madrid, Spain

[9] La Paz Univ Hosp, Pediat Nephrol Dept, Madrid, Spain

[10] La Paz Univ Hosp, Pediat Cardiol Dept, Madrid, Spain

[11] La Paz Univ Hosp, Pediat Hematooncol Dept, Madrid, Spain

[12] La Paz Univ Hosp, Pediat Pneumol Dept, Madrid, Spain

[13] Univ Lisbon, Hosp Santa Maria, Pediat Nephrol & Kidney Transplantat Unit, Dept Pediat,Fac Med, Lisbon, Portugal

[14] Ctr Hosp Porto, Ctr Materno Infantil Norte, Serv Pediat, Dept Pediat Nephrol, Porto, Portugal

[15] Ctr Hosp & Univ Coimbra, Dept Pediat Surg, Coimbra, Portugal

[16] Childrens Mem Hlth Inst, Dept Pediat Surg & Organ Transplantat, Warsaw, Poland

[17] Hosp Kremlin Bicetre, Dept Pediat Surg, Le Kremlin Bicetre, France

[18] Univ Paris 05, Hop Necker Enfants Malad, AP HP, Serv Pediat Nephrol, Paris, France

[19] Univ Paris Ctr, Hop Necker Enfants Malad, AP HP,Pediat Hepatol Unit, Reference Ctr Biliary Atresia & Genet Cholestasis, Paris, France

[20] ISMETT UPMC Palermo, Pediat Hepatol & Liver Transplantat, Palermo, Italy

[21] Karolinska Univ Hosp, Dept Transplantat Surg, Stockholm, Sweden

[22] Karolinska Inst, Karolinska Univ Hosp, CLINTEC, Dept Pediat Hepatol, Stockholm, Sweden

[23] Karolinska Univ Hosp, Dept Pediat Nephrol, Stockholm, Sweden

[24] Kings Coll Hosp London, Kings Coll London, Pediat Liver Gastrointestinal & Nutr Ctr, Sch Med, London, England

[25] Hannover Med Sch, Childrens Hosp, Div Pediat Gastroenterol & Hepatol, Hannover, Germany

[26] Hannover Med Sch, Clin Pediat Pneumol Allergol & Neonatol, Hannover, Germany

[27] Hosp Papa Giovanni XXIII, Ctr Pediat Hepatol Gastroenterol & Transplantat, Bergamo, Italy

[28] Bambino Gesu Children Hosp, Dept Gastroenterol & Hepatol, Rome, Italy

[29] Skane Univ Hosp, Dept Pediat, Sect Pediat Oncol Hematol, Lund, Sweden

[30] Univ Catholique Louvain UCLouvain, Inst Rech Expt & Clin, Unite PEDI, Lab Hepatol Pediat & Therapie Cellulaire, Brussels, Belgium

[31] Univ Catholique Louvain UCLouvain, Clin Univ St Luc, Dept Pediat, Serv Gastroenterol & Hepatol Pediat, Brussels, Belgium

[32] Prinses Maxima Ctr, Pediat Blood & Marrow Transplantat Program, Utrecht, Netherlands

[33] Vilnius Univ, Nephrol Ctr, Fac Med, Vilnius, Lithuania

[34] Vilnius Univ Hosp, Childrens Hosp, Ctr Pediat Oncol & Haematol, Vilnius, Lithuania

来源：

CLINICAL TRANSPLANTATION | 2020年 / 34卷 / 10期

关键词：

adolescents; children; coronavirus disease 2019; COVID-19; hematopoietic stem cell transplantation; pediatric transplantation; post-transplant management; SARS-CoV-2; solid organ transplantation; young;

D O I：

10.1111/ctr.14063

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 outbreak on pediatric transplant activity and healthcare practices in both solid organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT). The replies of 30 professionals from 18 centers in Europe were collected. Twelve of 18 centers (67%) showed a reduction in their usual transplant activity. Additionally, outpatient visits have been modified and restricted to selected ones, and the use of telemedicine tools has increased. Additionally, a total of 14 COVID-19 pediatric transplanted patients were identified at the time of the survey, including eight transplant recipients and six candidates for transplantation. Only two moderate-severe cases were reported, both in HSCT setting. These survey results demonstrate the limitations in healthcare resources for pediatric transplantation patients during early stages of this pandemic. COVID-19 disease is a major worldwide challenge for the field of pediatric transplantation, where there will be a need for systematic data collection, encouraging regular discussions to address the long-term consequences for pediatric transplantation candidates, recipients, and their families.

引用

页数：8

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