Type 2 diabetes: ceramides as a therapeutic target?

被引:2
作者
Hajduch, Eric [1 ,2 ,3 ]
Bourron, Olivier [1 ,2 ,4 ]
机构
[1] INSERM, Ctr Rech Cordeliers, UMR S 872, F-75006 Paris, France
[2] Univ Paris 06, UMR S 872, F-75006 Paris, France
[3] Univ Paris 05, UMR S 872, F-75006 Paris, France
[4] Hop La Pitie Salpetriere, AP HP, Dept Diabetologieet Malad Metab, Paris, France
关键词
Akt; beta-cells; ceramide synthase; CerS; insulin signaling; lipid; palmitate; PKB; PKC zeta/lambda; PP2A; sphingolipid; INSULIN-RESISTANCE; ADIPOSE-TISSUE; METABOLISM; MECHANISMS; MELLITUS; PARADOX;
D O I
10.2217/clp.13.65
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:607 / 609
页数:3
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