Water soluble nanocarbon materials: a panacea for all?

被引:41
作者
Eswaran, S. V. [1 ]
机构
[1] Reg Ctr Biotechnol, NCR Biotech Sci Cluster, Faridabad 121001, India
来源
CURRENT SCIENCE | 2018年 / 114卷 / 09期
关键词
Nanobiotechnology; nanomaterials; theranostics; targeted drug delivery; FULLERENES; C-60;
D O I
10.18520/cs/v114/i09/1846-1850
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The low solubility of nanocarbon materials (fullerenes, CNTs and graphene) has restricted their widespread commercial use. Functionalization, however, helps overcome this major limitation. Much work has been documented recently on water soluble fullerenes (FWS) in treating cancer (e.g. breast cancer), tumours, arthritis, Parkinson's, influenzas and HIV-AIDS. Even an aqueous nasal spray to combat Alzheimer's has been advocated. A recent US patent shows that FWS, based on its anti-oxidant activity, is a powerful Radical Oxygen Scavenger. FWS have been used in X-ray imaging, as MRI Contrast Agents (MRI-CA), to make solar cells and could help produce nanodevices and biosensors. This review examines this emerging field.
引用
收藏
页码:1846 / 1850
页数:5
相关论文
共 17 条
[1]   Functionalized fullerene (C60) as a potential nanomediator in the fabrication of highly sensitive biosensors [J].
Afreen, Sadia ;
Muthoosamy, Kasturi ;
Manickam, Sivakumar ;
Hashim, Uda .
BIOSENSORS & BIOELECTRONICS, 2015, 63 :354-364
[2]   Synthesis of starburst hexa(oligoanilinated) C60 using hexanitro[60]fullerene as a precursor [J].
Anantharaj, V ;
Wang, LY ;
Canteenwala, T ;
Chiang, LY .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (22) :3357-3366
[3]   Fullerene-Based Symmetry in Hibiscus rosa-sinensis Pollen [J].
Andrade, Kleber ;
Guerra, Sara ;
Debut, Alexis .
PLOS ONE, 2014, 9 (07)
[4]   Gadofullerene MRI contrast agents [J].
Bolskar, Robert D. .
NANOMEDICINE, 2008, 3 (02) :201-213
[5]   Applications of Functionalized Fullerenes in Tumor Theranostics [J].
Chen, Zhiyun ;
Ma, Lijing ;
Liu, Ying ;
Chen, Chunying .
THERANOSTICS, 2012, 2 (03) :238-250
[6]   Carboxyfullerene Neuroprotection Postinjury in Parkinsonian Nonhuman Primates [J].
Dugan, Laura L. ;
Tian, LinLin ;
Quick, Kevin L. ;
Hardt, Josh I. ;
Karimi, Morvarid ;
Brown, Chris ;
Loftin, Susan ;
Flores, Hugh ;
Moerlein, Stephen M. ;
Polich, John ;
Tabbal, Samer D. ;
Mink, Jonathan W. ;
Perlmutter, Joel S. .
ANNALS OF NEUROLOGY, 2014, 76 (03) :393-402
[7]   Dynamic Integration of Reward and Stimulus Information in Perceptual Decision-Making [J].
Gao, Juan ;
Tortell, Rebecca ;
McClelland, James L. .
PLOS ONE, 2011, 6 (03)
[8]   THE FORMATION OF FULLERENES: CLUES FROM NEW C60, C70, AND (POSSIBLE) PLANAR C24 DETECTIONS IN MAGELLANIC CLOUD PLANETARY NEBULAE [J].
Garcia-Hernandez, D. A. ;
Iglesias-Groth, S. ;
Acosta-Pulido, J. A. ;
Manchado, A. ;
Garcia-Lario, P. ;
Stanghellini, L. ;
Villaver, E. ;
Shaw, R. A. ;
Cataldo, F. .
ASTROPHYSICAL JOURNAL LETTERS, 2011, 737 (02)
[9]  
Garcia-Hernandez D. A., 2011, ASTROPHYS J LETT, V724, P1
[10]   Biomedical potential of the reactive oxygen species generation and quenching by fullerenes (C60) [J].
Markovic, Zoran ;
Trajkovic, Vladimir .
BIOMATERIALS, 2008, 29 (26) :3561-3573