THE AMERICAN UROLOGICAL ASSOCIATION SYMPTOM INDEX FOR BENIGN PROSTATIC HYPERPLASIA

被引:62
作者
Barry, Michael J. [1 ]
Fowler, Floyd J.
O'Leary, Michael P.
Bruskewitz, Reginald C., Jr.
Holtgrewe, H. Logan
Mebust, Winston K.
Cockett, Abraham T. K.
机构
[1] Massachusetts Gen Hosp, Med Practices Evaluat Ctr, Boston, MA 02114 USA
关键词
prostatic hypertrophy; prostatic diseases; statistics; TRANSURETHRAL PROSTATECTOMY;
D O I
10.1016/j.juro.2016.10.071
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
A symptom index for benign prostatic hyperplasia (BPH) was developed and validated by a multidisciplinary measurement committee of the American Urological Association (AUA). Validation studies were conducted involving a total of 210 BPH patients and 108 control subjects. The final AUA symptom index includes 7 questions covering frequency, nocturia, weak urinary stream, hesitancy, intermittence, incomplete emptying and urgency. On revalidation, the index was internally consistent (Cronbach's alpha = 0.86) and the score generated had excellent test-retest reliability (r = 0.92). Scores were highly correlated with subjects' global ratings of the magnitude of their urinary problem (r = 0.65 to 0.72) and powerfully discriminated between BPH and control subjects (receiver operating characteristic area 0.85). Finally, the index was sensitive to change, with preoperative scores decreasing from a mean of 17.6 to 7.1 by 4 weeks after prostatectomy (p<0,001), The AUA symptom index is clinically sensible, reliable, valid and responsive. It is practical for use in practice and for inclusion in research protocols.
引用
收藏
页码:S189 / S197
页数:9
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