Critical Care of Hematopoietic Stem Cell Transplant Patients

被引：7

作者：

Fornwalt, Rachael A. ^{[1
]}

Brigham, Emily P. ^{[2
]}

Stephens, R. Scott ^{[3
,4
]}

机构：

[1] Johns Hopkins Univ Hosp, Oncol Intens Care Unit, Johns Hopkins Sidney Kimmel Comprehens Canc Ctr, Harry & Jeanette Weinberg Bldg,Pod 5C, Baltimore, MD 21231 USA

[2] Johns Hopkins Univ, Dept Med, Div Pulm & Crit Care Med, Oncol Intens Care Unit, 1830 East Monument St,5th Floor, Baltimore, MD 21205 USA

[3] Johns Hopkins Univ, Dept Med, Oncol Intens Care Unit, Div Pulm & Crit Care Med, 1800 Orleans St,Suite 9121 Zayed Tower, Baltimore, MD 21287 USA

[4] Johns Hopkins Univ, Dept Oncol, Oncol Intens Care Unit, Div Pulm & Crit Care Med, 1800 Orleans St,Suite 9121 Zayed Tower, Baltimore, MD 21287 USA

来源：

CRITICAL CARE CLINICS | 2021年 / 37卷 / 01期

关键词：

Hematopoietic stem cell transplant; Bone marrow transplant; Acute respiratory distress syndrome; Neutropenic sepsis; Graft-versus-host disease; Cytokine release syndrome; Engraftment syndrome; Acute renal failure; HYPOXEMIC RESPIRATORY-FAILURE; CLINICAL-PRACTICE GUIDELINE; VERSUS-HOST-DISEASE; EXTRACORPOREAL MEMBRANE-OXYGENATION; BONE-MARROW-TRANSPLANTATION; NEUTROPENIC PATIENTS; IMMUNOCOMPROMISED PATIENTS; NONINVASIVE VENTILATION; TRANSFUSION THRESHOLDS; PLATELET-TRANSFUSION;

D O I：

10.1016/j.ccc.2020.08.002

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Life-threatening complications are frequent after hematopoietic stem cell transplant (HSCT), and optimum critical care is essential to ensuring good outcomes. The immunologic consequences of HSCT result in a markedly different host response to critical illness. Infection is the most common cause of critical illness but noninfectious complications are frequent. Respiratory failure or sepsis are the typical presentations but the sequelae of HSCT can affect nearly any organ system. Pattern recognition can facilitate anticipation and early intervention in post-HSCT critical illness. HSCT critical care is a multidisciplinary endeavor. Continued investigation and focus on process improvement will continue to improve outcomes. © 2020 Elsevier Inc.

引用

页码：29 / 46

页数：18

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