Quantitative Determination in Aqueous Solutions of Physiologically Active Copolymers of N-Vinylpyrrolidone and 2-Methyl-5-Vinylpyridine

被引：0

作者：

Kedik, S. A. ^{[1
]}

Panov, A. V. ^{[1
]}

Sakaeva, I. V. ^{[2
]}

Kochkina , Yu. V. ^{[1
]}

Eremin, D. V. ^{[1
]}

Suslov, V. V. ^{[1
]}

Zaitsev, M. A. ^{[3
]}

机构：

[1] Inst Pharmaceut Technol, Moscow 121353, Russia

[2] Minist Russian Federat Publ Hlth, State Sci Ctr Drug Expertise & Control, Moscow 127051, Russia

[3] Russian Acad Sci, Space Res Inst, Moscow 117997, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2014年 / 47卷 / 10期

关键词：

quantitative determination; N-vinylpyrrolidone and 2-methyl-5-vinylpyridine copolymer; aqueous solutions;

D O I：

10.1007/s11094-014-1008-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Techniques for quantitative determination of N-vinylpyrrolidone and 2-methyl-5-vinylpyridine copolymers in aqueous solutions were developed. The spectrophotometric technique allowed the copolymer concentration in dilute solutions (0.8 - 1.2 mg/mL) to be determined even in the presence of the interfering additive merthiolate. The refractometric technique was simpler and allowed the copolymer concentration in concentrated solutions (> 1 mass%) to be determined.

引用

页码：569 / 571

页数：3