Imaging biomarkers and biotypes for depression

被引：29

作者：

Wager, Tor D. ^{[1
]}

Woo, Choong-Wan ^{[1
]}

机构：

[1] Univ Colorado, Dept Psychol & Neurosci, Boulder, CO 80309 USA

来源：

NATURE MEDICINE | 2017年 / 23卷 / 01期

关键词：

D O I：

10.1038/nm.4264

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new study identifies four distinct 'biotypes' of depression on the basis of fMRI resting-state functional connectivity in a diverse sample of more than 1,000 individuals. The biotypes are diagnostic of depression and predict treatment response.

引用

页码：16 / 17

页数：2

共 9 条

[1]

Carter MJ, 2014, THER RECREAT J, V48, P275

[2] A New Initiative on Precision Medicine [J].

Collins, Francis S. ;

Varmus, Harold .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (09) :793-795

[3] Resting-state connectivity biomarkers define neurophysiological subtypes of depression [J].

Drysdale, Andrew T. ;

Grosenick, Logan ;

Downar, Jonathan ;

Dunlop, Katharine ;

Mansouri, Farrokh ;

Meng, Yue ;

Fetcho, Robert N. ;

Zebley, Benjamin ;

Oathes, Desmond J. ;

Etkin, Amit ;

Schatzberg, Alan F. ;

Sudheimer, Keith ;

Keller, Jennifer ;

Mayberg, Helen S. ;

Gunning, Faith M. ;

Alexopoulos, George S. ;

Fox, Michael D. ;

Pascual-Leone, Alvaro ;

Voss, Henning U. ;

Casey, B. J. ;

Dubin, Marc J. ;

Liston, Conor .

NATURE MEDICINE, 2017, 23 (01) :28-38

[4] Machine learning: Trends, perspectives, and prospects [J].

Jordan, M. I. ;

Mitchell, T. M. .

SCIENCE, 2015, 349 (6245) :255-260

[5] Machine learning classifiers and fMRI: A tutorial overview [J].

Pereira, Francisco ;

Mitchell, Tom ;

Botvinick, Matthew .

NEUROIMAGE, 2009, 45 (01) :S199-S209

[6] DSM-5 Field Trials in the United States and Canada, Part II: Test-Retest Reliability of Selected Categorical Diagnoses [J].

Regier, Darrel A. ;

Narrow, William E. ;

Clarke, Diana E. ;

Kraemer, Helena C. ;

Kuramoto, S. Janet ;

Kuhl, Emily A. ;

Kupfer, David J. .

AMERICAN JOURNAL OF PSYCHIATRY, 2013, 170 (01) :59-70

[7] BEING SANE IN INSANE PLACES [J].

ROSENHAN, DL .

SCIENCE, 1973, 179 (4070) :250-258

[8] Developing Constructs for Psychopathology Research: Research Domain Criteria [J].

Sanislow, Charles A. ;

Pine, Daniel S. ;

Quinn, Kevin J. ;

Kozak, Michael J. ;

Garvey, Marjorie A. ;

Heinssen, Robert K. ;

Wang, Philip Sung-En ;

Cuthbert, Bruce N. .

JOURNAL OF ABNORMAL PSYCHOLOGY, 2010, 119 (04) :631-639

[9] An fMRI-Based Neurologic Signature of Physical Pain [J].

Wager, Tor D. ;

Atlas, Lauren Y. ;

Lindquist, Martin A. ;

Roy, Mathieu ;

Woo, Choong-Wan ;

Kross, Ethan .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (15) :1388-1397

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