In a new situation how to meet the needs of students of medical knowledge, train excellent medical workers for social, it is particularly important that improve teaching of human anatomy as the medical main course. Department of Anatomy has some useful exploration and reform of human anatomy laboratory management and experimental teaching.Through improved the required hardware and software environment of the experimental class, increased open time of laboratory to students, the implementation of PBL (Problem Based Learning) and TBL (Team Based Learning) teaching combined mode and improved the form of examination lead to good results in experimental teaching.