Intracapsular (in situ) carcinoma ex pleomorphic adenoma with unusual clinical and histological features

被引：4

作者：

Logasundaram, Rajesh ^{[1
]}

Amarawickrama, Himan ^{[2
]}

Premachandra, Don ^{[2
]}

Hellquist, Henrik ^{[1
]}

机构：

[1] Norfolk & Norwich Hosp, Hosp NHS Trust, Dept Histopathol, Cotman Ctr, Norwich NR4 7UB, Norfolk, England

[2] James Paget Hosp NHS Trust, Dept ENT Surg, Great Yarmouth, England

来源：

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 2008年 / 265卷 / 12期

关键词：

Pleomorphic adenoma; Intracapsular carcinoma ex pleomorphic adenoma; Myoepithelial carcinoma;

D O I：

10.1007/s00405-008-0615-y

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Carcinoma ex pleomorphic adenoma poses a challenge to diagnosis and treatment. Herein we describe an extremely unusual case, which presented initially as an intracapsular carcinoma ex pleomorphic adenoma in the right parotid gland. The first recurrence, after an interval of 8 years, showed only recurrence of the benign component. Five years later, a myoepithelial carcinoma arose from the same site. No ductal carcinoma as seen in the initial intracapsular carcinoma ex pleomorphic adenoma was identified. This case report elucidates the atypical clinical behaviour and interesting histological features encountered within this group of salivary neoplasm.

引用

页码：1563 / 1566

页数：4

共 28 条

[1] Alos L, 1996, SEMIN DIAGN PATHOL, V13, P138
[2] [Anonymous], 2005, PATHOLOGY GENETICS H
[3] Auclair PL, 1996, MODERN PATHOL, V9, P652
[4] Bradley Patrick J, 2005, Curr Opin Otolaryngol Head Neck Surg, V13, P123, DOI 10.1097/01.moo.0000153450.87288.2a
[5] Noninvasive and minimally invasive carcinoma ex mixed tumor - A clinicopathologic and ploidy study of 12 patients with major salivary tumors of low (or no?) malignant potential
Brandwein, M
Huvos, AG
Dardick, I
Thomas, MJ
Theise, ND
[J]. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1996, 81 (06): : 655 - 664
[6] Non-invasive (intracapsular) carcinoma ex pleomorphic adenoma:: recognition of focal carcinoma by HER-2/neu and MIB1 immunohistochemistry
Di Palma, S
Skálová, A
Vanìèek, T
Simpson, RHW
Stárek, I
Leivo, I
[J]. HISTOPATHOLOGY, 2005, 46 (02) : 144 - 152
[7] DIPALMA S, 1993, VIRCHOWS ARCH A, V423, P389
[8] El-Mofty SK, 1994, INT J SURG PATHOL, V2, P133
[9] Ellis GL, 1996, ATLAS TUMOR PATHOL, P155
[10] BENIGN METASTATIC MIXED TUMORS OR UNRECOGNIZED SALIVARY CARCINOMAS
ELNAGGAR, A
BATSAKIS, JG
KESSLER, S
[J]. JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1988, 102 (09) : 810 - 812

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