Computational modelling of blood flow in side arterial branches after stenting of cerebral aneurysms

被引:26
作者
Appanaboyina, Sunil [1 ]
Mut, Fernando [1 ]
Loehner, Rainald [2 ]
Scrivano, Esteban [3 ]
Miranda, Carlos [3 ]
Lylyk, Pedro [3 ]
Putman, Christopher [4 ]
Cebral, Juan [2 ]
机构
[1] George Mason Univ, Computat & Data Sci Dept, Fairfax, VA 22030 USA
[2] George Mason Univ, Ctr Computat & Fluid Dynam, Fairfax, VA 22030 USA
[3] Clin ENERI, Buenos Aires, DF, Argentina
[4] Inova Fairfax Hosp, Falls Church, VA USA
关键词
cerebral aneurysms; haemodynamics; stenting; perforators; image-based modelling;
D O I
10.1080/10618560802495255
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
The major concern with the use of stents as flow diverters for the treatment of intracranial aneurysms is the potential occlusion of a perforating artery or other side branches which can cause ischemic strokes. This article presents image-based patient-specific models of stented cerebral aneurysms in which a small side artery has been jailed by the stent mesh. The results indicate that, because of the large resistances of the distal vascular beds which dominate the flow divisions among the different arterial branches, the flow reduction in jailed side branches is quite small even when a large percentage of the inlet area of these branches has been blocked. This suggests that unless the side branch is completely occluded, it will likely maintain its normal blood flow. Although this conclusion eases the concern of stenting cerebral aneurysms, a complete occlusion can still be caused depending on the conformability characteristics of the stents.
引用
收藏
页码:669 / 676
页数:8
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