Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties

被引：71
|
作者：
Iqbal, Nida [1 ]
Kadir, Mohammed Rafiq Abdul [1 ]
Malek, Nik Ahmad Nizam Nik [2 ,3 ]
Mahmood, Nasrul Humaimi [1 ]
Murali, Malliga Raman [4 ]
Kamarul, Tunku [4 ]
机构：
[1] Univ Teknol Malaysia, Med Implant Technol Grp MEDITEG, Fac Biomed Engn & Hlth Sci, Skudai 81310, Johor Darul Tak, Malaysia
[2] Univ Teknol Malaysia, Fac Biosci & Bioengn, Skudai 81310, Johor Darul Tak, Malaysia
[3] Univ Teknol Malaysia, Inst Ibnu Sina Fundamental Sci Studies, Skudai 81310, Johor Darul Tak, Malaysia
[4] Univ Malaya, Tissue Engn Grp, Dept Orthopaed Surg, NOCERAL,Fac Med, Kuala Lumpur 50603, Malaysia
来源：
MATERIALS LETTERS | 2012年 / 89卷
关键词：
Biomaterial; Hydroxyapatite; Nano particles; Microwave irradiation; Antibacterial activity; SUBSTITUTED HYDROXYAPATITE;
D O I：
10.1016/j.matlet.2012.08.057
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid method for synthesizing nano-sized Ag-doped hydroxyapatite (Ag-HA) [Ca10-xAgx(PO4)(6)(OH)(2)] (x=0.03-0.5) using microwave irradiation for 10 min at 800 W is proposed. The materials were characterized using XRD, FTIR, FESEM and EDX. Antibacterial behavior of the Ag-HA samples were evaluated using disc diffusion technique and results demonstrated good activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：118 / 122
页数：5
相关论文
共 50 条
  • [21] Rapid microwave assisted synthesis of hydroxyapatite
    Vaidhyanathan, B
    Rao, KJ
    BULLETIN OF MATERIALS SCIENCE, 1996, 19 (06) : 1163 - 1165
  • [22] Physicochemical and antimicrobial properties of silver-doped hydroxyapatite collagen biocomposite
    Predoi, Daniela
    Iconaru, Simona Liliana
    Albu, Madalina
    Petre, Cristian Catalin
    Jiga, Gabriel
    POLYMER ENGINEERING AND SCIENCE, 2017, 57 (06) : 537 - 545
  • [23] Synthesis of antimicrobial monophase silver-doped hydroxyapatite nanopowders for bone tissue engineering
    Stanic, Vojislav
    Janackovic, Djordje
    Dimitrijevic, Suzana
    Tanaskovic, Sladjana B.
    Mitric, Miodrag
    Pavlovic, Mirjana S.
    Krstic, Aleksandra
    Jovanovic, Dragoljub
    Raicevic, Slavica
    APPLIED SURFACE SCIENCE, 2011, 257 (09) : 4510 - 4518
  • [24] Antibacterial effects of silver-doped hydroxyapatite thin films sputter deposited on titanium
    Trujillo, Nathan A.
    Oldinski, Rachael A.
    Ma, Hongyan
    Bryers, James D.
    Williams, John D.
    Popat, Ketul C.
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2012, 32 (08): : 2135 - 2144
  • [25] The Physical and Antimicrobial Properties of Silver Doped Hydroxyapatite Sintered by Microwave and Conventional Sintering
    Shi, Xingyuan
    Zhou, Jian
    Liu, Guizhen
    Wang, Lin
    JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2017, 27 (04) : 955 - 961
  • [26] Synthesis and Characterization of Hydroxyapatite/Silver Nanoparticles Composites and Their Antibacterial Properties for Dental Filling Application
    Murugan, Lakshmanan
    Kim, Sung-Min
    Rajesh, Arjun
    Arunachalam, Kannappan
    Davoodbasha, MubarakAli
    Kim, Jung-Wan
    Lee, Sang-Yul
    BIONANOSCIENCE, 2023, 13 (04) : 2215 - 2224
  • [27] Synthesis and Characterization of Hydroxyapatite/Silver Nanoparticles Composites and Their Antibacterial Properties for Dental Filling Application
    Lakshmanan Murugan
    Sung-Min Kim
    Arjun Rajesh
    Kannappan Arunachalam
    MubarakAli Davoodbasha
    Jung-Wan Kim
    Sang-Yul Lee
    BioNanoScience, 2023, 13 (4) : 2215 - 2224
  • [28] Synthesis and characterization of Eu-doped hydroxyapatite through a microwave assisted microemulsion process
    Yang, Chun
    Yang, Piaoping
    Wang, Wenxin
    Gai, Shili
    Wang, Jun
    Zhang, Milin
    Lin, Jun
    SOLID STATE SCIENCES, 2009, 11 (11) : 1923 - 1928
  • [29] Synthesis and characterization of silver nanoparticles-doped hydroxyapatite/alginate microparticles with promising cytocompatibility and antibacterial properties
    Zhou, Qiuju
    Wang, Tianwen
    Wang, Can
    Wang, Zheng
    Yang, Yanan
    Li, Pei
    Cai, Ruihua
    Sun, Meng
    Yuan, Hongyu
    Nie, Lei
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2020, 585
  • [30] Novel continuous microwave assisted flow synthesis of nanosized manganese substituted hydroxyapatite
    Anwar, Aneela
    Akbar, Samina
    CERAMICS INTERNATIONAL, 2018, 44 (09) : 10878 - 10882
12345