Towards the development of latent heat storage electrodes for electroporation-based therapies

被引：10

作者：

Arena, Christopher B. ^{[1
]}

Mahajan, Roop L. ^{[2
]}

Rylander, Marissa Nichole ^{[3
]}

Davalos, Rafael V. ^{[1
]}

机构：

[1] Virginia Tech, Bioelectromech Syst Lab, Wake Forest Sch Biomed Engn & Sci, Blacksburg, VA 24061 USA

[2] Virginia Tech, ICTAS, Blacksburg, VA 24061 USA

[3] Virginia Tech, Tissue Engn Nanotechnol & Canc Res Lab, Wake Forest Sch Biomed Engn & Sci, Dept Mech Engn, Blacksburg, VA 24061 USA

来源：

APPLIED PHYSICS LETTERS | 2012年 / 101卷 / 08期

基金：

美国国家科学基金会;

关键词：

THERMAL-ENERGY STORAGE; PHASE-CHANGE MATERIALS; IRREVERSIBLE ELECTROPORATION; TISSUE ABLATION;

D O I：

10.1063/1.4747332

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Phase change materials (PCMs) capable of storing a large amount of heat upon transitioning from the solid-to-liquid state have been widely used in the electronics and construction industries for mitigating temperature development. Here, we show that they are also beneficial for reducing the peak tissue temperature during electroporation-based therapies. A numerical model is developed of irreversible electroporation (IRE) performed with hollow needle electrodes filled with a PCM. Results indicate that this electrode design can be utilized to achieve large ablation volumes while reducing the probability for thermal damage. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4747332]

引用

页数：4

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