MicroRNAs and endocrine biology

被引：127
作者：
Cuellar, TL [1 ]
McManus, MT [1 ]
机构：
[1] Univ Calif San Francisco, Ctr Diabet, Dept Microbiol & Immunol, San Francisco, CA 94122 USA
来源：
JOURNAL OF ENDOCRINOLOGY | 2005年 / 187卷 / 03期
关键词：
D O I：
10.1677/joe.1.06426
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
microRNAs (miRNAs) are highly conserved, non-codnig RNAs that powerfully regulate gene expression at the post-transcriptional level. These fascinating molecules play essential roles in many biological processes in mammals, including insulin Secretion, B-cell development, and adipocyte differentiation. This review provides a general background regarding current knowledge about miRNA blogenesis and the potential contributions of these RNAs to endocrine function.
引用
收藏
页码：327 / 332
页数：6
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