Synthesis of Polysubstituted Naphthalenes by Iron-Catalyzed [2+2+2] Annulation of Grignard Reagents with Alkynes

被引：32

作者：

Ilies, Laurean ^{[1
]}

Matsumoto, Arimasa ^{[1
]}

Kobayashi, Motoaki ^{[1
]}

Yoshikai, Naohiko ^{[1
]}

Nakamura, Eiichi ^{[1
]}

机构：

[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

来源：

SYNLETT | 2012年 / 16期

基金：

日本学术振兴会;

关键词：

alkynes; annulation; C-H bond activation; iron; naphthalene; SUBSTITUTED NAPHTHALENES; INTERNAL ALKYNES; ORTHO-ARYLATION; ARYL IODIDES; ARYLMAGNESIATION; ANNELATION; ACTIVATION; IMINES; ACENES; ARENE;

D O I：

10.1055/s-0032-1317077

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iron catalyzes the oxidative [2+2+2] annulation of an arylmagnesium compound with two molecules of an internal alkyne via C-H bond activation at 0 degrees C to produce polysubstituted naphthalene.

引用

页码：2381 / 2384

页数：4

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