Triple expressor lymphoma in a kidney transplant patient

被引:0
作者
Aranguiz, Natalia [1 ,2 ]
Vega, Jorge [3 ,4 ]
机构
[1] Hosp Dr Gustavo Fricke, Serv Med, Secc Hematol, Vina Del Mar, Chile
[2] Hosp Naval A Nef, Serv Hematooncol, Vina Del Mar, Chile
[3] Hosp Naval A Nef, Serv Med, Secc Nefrol, Vina Del Mar, Chile
[4] Univ Valparaiso, Escuela Med, Dept Med, Valparaiso, Chile
关键词
Drug Therapy; Kidney Transplantation; Lymphoma; NonHodgkin; Lymphoproliferative Disorders; B-CELL LYMPHOMA; SOLID-ORGAN TRANSPLANTATION; DOUBLE-HIT; MYC; BCL2;
D O I
10.4067/s0034-98872019000200247
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients transplanted from solid organs have an increased risk of cancer, especially lymphomas. Lymphomas correspond to 4 to 5% of malignant neoplasms in the general population and in solid organ transplant patients it reaches an incidence of 21%. The incidence of non-Hodgkin lymphomas is 10 times higher than in the non-transplanted population. We report the case of a 68-year-old man with a kidney transplant who 6 years after transplantation, developed a non-Hodgkin diffuse large cells B lymphoma with lymph node and pulmonary involvement, with markers of very poor prognosis (triple MYC expressor, BCL2 and BCL6). and its evolution with chemotherapy with DA R EPOCH.
引用
收藏
页码:247 / 250
页数:4
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