Novel and efficient method for the silylation of hydroxyl groups with hexamethyldisilazane (HMDS) under solvent-free and neutral conditions

被引：145

作者：

Azizi, N ^{[1
]}

Saidi, MR ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

ORGANOMETALLICS | 2004年 / 23卷 / 06期

关键词：

D O I：

10.1021/om0341505

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Various alcohols and phenols were silylated to trimethylsilyl ethers with hexamethyldisilazane in the presence of solid lithium perchlorate under very mild, neutral, and solvent-free conditions in good to excellent yields.

引用

页码：1457 / 1458

页数：2

共 17 条

[1] A new protocol for the Baylis-Hillman reaction: the reaction of iminium salts prepared in situ with methyl acrylate [J].

Azizi, N ;

Saidi, MR .

TETRAHEDRON LETTERS, 2002, 43 (24) :4305-4308

[2]

Brook M. A, 2000, SILICON ORGANIC ORGA

[3]

Gauuret P., 1996, SYNTHETIC COMMUN, V26, P707

[4]

Greene T. W., 1999, PROTECTIVE GROUPS OR

[5]

HOSOMI A, 1981, CHEM LETT, V85, P880

[6] Mild and highly efficient method for the silylation of alcohols using hexamethyldisilazane catalyzed by iodine under nearly neutral reaction conditions [J].

Karimi, B ;

Golshani, B .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (21) :7228-7230

[7] PREPARATION AND PROPERTIES OF TRIMETHYLSILYL ETHERS AND RELATED COMPOUNDS [J].

LANGER, SH ;

CONNELL, S ;

WENDER, I .

JOURNAL OF ORGANIC CHEMISTRY, 1958, 23 (01) :50-58

[8] Silylation of hydroxy groups with HMDS under microwave irradiation and solvent-free conditions [J].

Mojtahedi, MM ;

Saidi, MR ;

Bolourtchian, M ;

Heravi, MM .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2002, 177 (02) :289-292

[9] USE OF ALLYLSILANES AS A NEW TYPE OF SILYLATING AGENT FOR ALCOHOLS AND CARBOXYLIC-ACIDS [J].

MORITA, T ;

OKAMOTO, Y ;

SAKURAI, H .

TETRAHEDRON LETTERS, 1980, 21 (09) :835-838

[10] SYNTHETIC METHODS AND REACTIONS .104. SILYLATIONS WITH INSITU GENERATED TRIMETHYLSILYL TRIFLATE REAGENT SYSTEMS [J].

OLAH, GA ;

HUSAIN, A ;

GUPTA, BGB ;

SALEM, GF ;

NARANG, SC .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (25) :5212-5214

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