Efficacy of PD 180988, a selective endothelin ETA receptor antagonist, in acute and chronic hypoxia induced pulmonary hypertension.

被引：0
|
作者：
Schroeder, RL [1 ]
Welch, KM [1 ]
Bryant, JW [1 ]
Repine, JT [1 ]
Cheng, KM [1 ]
Keiser, JA [1 ]
Haleen, SJ [1 ]
机构：
[1] Warner Lambert Parke Davis, Parke Davis Pharmaceut Res Div, Ann Arbor, MI 48105 USA
来源：
FASEB JOURNAL | 1999年 / 13卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A40 / A40
页数：1
相关论文
共 50 条
  • [1] The ETA receptor antagonist PD180988 selectively reverses the pulmonary vasoconstrictor response to hypoxia in the lamb
    Coe, JY
    Coceani, F
    Haleen, S
    Welch, KM
    CIRCULATION, 2000, 102 (18) : 558 - 558
  • [2] A novel and selective endothelin ETA receptor antagonist YM598 prevents the development of chronic hypoxia-induced pulmonary hypertension in rats
    Yuyama, H
    Fujimori, A
    Sanagi, M
    Koakutsu, A
    Noguchi, Y
    Sudoh, K
    Sasamata, M
    Miyata, K
    VASCULAR PHARMACOLOGY, 2005, 43 (01) : 40 - 46
  • [3] Effects of a selective endothelin A (ETA) receptor antagonist on GBS-induced pulmonary hypertension in newborn piglets
    Peng, JH
    Ladino, J
    Hehre, D
    Bancalari, E
    Suguihara, C
    PEDIATRIC RESEARCH, 2003, 53 (04) : 432A - 432A
  • [4] ENDOTHELIN-A RECEPTOR ANTAGONIST PREVENTS ACUTE HYPOXIA-INDUCED PULMONARY-HYPERTENSION IN THE RAT
    OPARIL, S
    CHEN, SJ
    MENG, QC
    ELTON, TS
    YANO, M
    CHEN, YF
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 1995, 268 (01) : L95 - L100
  • [5] Pharmacodynamics of PD 156707, a selective endothelin receptor-A (ET(A)) antagonist, in acute hypoxic pulmonary hypertension (PH).
    Keiser, JA
    Schroeder, RL
    Hallak, H
    Uprichard, ACG
    Doherty, AM
    Haleen, SJ
    FASEB JOURNAL, 1997, 11 (03): : 206 - 206
  • [6] The endothelin-A-receptor antagonist PD180988 (CI-1034) selectively reverses the pulmonary vasoconstrictor response to hypoxia in the lamb
    Coe, Y
    Haleen, SJ
    Welch, KM
    Coceani, F
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2000, 36 : S331 - S333
  • [7] Ambrisentan -: Treatment of pulmonary arterial hypertension endothelin ETA receptor antagonist
    Sorbera, LA
    Castañer, J
    DRUGS OF THE FUTURE, 2005, 30 (08) : 765 - 770
  • [8] The ET-A receptor antagonist PD180988 selectively reverses the pulmonary vasoconstrictor response to hypoxia in the lamb
    Coe, JY
    Timmisky, J
    Coceani, F
    Haleen, SJ
    Welch, KM
    PEDIATRIC RESEARCH, 2000, 47 (04) : 40A - 40A
  • [9] Prolonged endothelin A receptor blockade attenuates chronic intrauterine pulmonary hypertension.
    Ivy, DD
    Parker, TA
    Ziegler, JW
    Galan, HL
    Kinsella, JP
    Abman, SH
    PEDIATRIC RESEARCH, 1996, 39 (04) : 1994 - 1994
  • [10] Effects of a nebulized endothelin A (ETA) receptor antagonist on GBS-induced pulmonary hypertension in newborn piglets
    Peng, JH
    Ladino, J
    Navarrete, C
    Bancalari, E
    Suguihara, C
    PEDIATRIC RESEARCH, 2003, 53 (04) : 314A - 314A
12345