Role of integrins in the periodontal ligament: organizers and facilitators

被引：34

作者：

Barczyk, Malgorzata

Bolstad, Anne Isine

Gullberg, Donald

机构：

来源：

PERIODONTOLOGY 2000 | 2013年 / 63卷 / 01期

关键词：

GROWTH-FACTOR-BETA; ACTIVATES LATENT TGF-BETA-1; EHLERS-DANLOS-SYNDROME; COLLAGEN TYPE-I; EXTRACELLULAR-MATRIX; ALPHA-11-BETA-1; INTEGRIN; 3-DIMENSIONAL COLLAGEN; CELL-ADHESION; CATHEPSIN K; MARFAN-SYNDROME;

D O I：

10.1111/prd.12027

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The periodontal ligament is the tissue that connects teeth to bone. The periodontal ligament is a fascinating tissue from a cell biologist's point of view, and because of its special properties and stem-cell content it has also come into the limelight in emerging fields of regenerative medicine. An increased range of genetically modified mouse models offer new tools for studying molecular mechanisms of tooth development. However, owing to species-specific organization of the tooth apparatus, the use of genetic animal models to study the role of the periodontal ligament in normal human tooth physiology and tooth pathology is challenging.

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页码：29 / 47

页数：19

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