Microwave-assisted, montmorillonite K-10 catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

被引：71

作者：

Reddy, Mudumala Veeranarayana ^{[1
]}

Reddy, Gangireddy Chandra Sekhar ^{[2
]}

Jeong, Yeon Tae ^{[1
]}

机构：

[1] Pukyong Natl Univ, Dept Image Sci & Engn, Pusan 608737, South Korea

[2] Pusan Natl Univ, Dept Polymer Sci & Engn, WCU Ctr Synthet Polymer Bioconjugate Hybrid Mat, Pusan 609735, South Korea

来源：

TETRAHEDRON | 2012年 / 68卷 / 34期

关键词：

2H-indazolo[2,1-b]phthalazine-triones; Montmorillonite K-10; Microwave irradiation; Solvent-free reaction; ONE-POT; IONIC LIQUID; PHTHALAZINE-1,4-DIONE; GREEN; ACID;

D O I：

10.1016/j.tet.2012.06.045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, rapid, and green synthesis of 2H-indazolo[2,1-b]phthalazine-triones has been accomplished under solvent-free conditions by the reaction of phthalhydrazide, aldehydes and 5,5-dimethylcyclohexane-1,3-dione. This approach exploits the synthetic potential of microwave irradiation and Montmorillonite K-10 combination and offers many advantages, such as excellent product yields, shorter reaction time, reusable catalyst, easy isolation of products, and environmentally benign reaction conditions. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：6820 / 6828

页数：9

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