One-pot preparation of 1,2-aminoalcohols or pyrroles by CeCl3•7 H2O-mediated Barbier reactions of N,N′-bis[(S)-1-phenylethyl]ethanediimine

被引：0

作者：

Martelli, G ^{[1
]}

Morri, S ^{[1
]}

Savoia, D ^{[1
]}

机构：

[1] Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

来源：

SYNLETT | 2002年 / 01期

关键词：

1,2-aminoalcohols; cerium trichloride; 1,2-diamines; pyrroles; stereoselective synthesis;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,2-Aminoalcohols or pyrroles were obtained from N,N'-bis [(S)-1-phenylethyliethanediimine by a one-pot procedure involving two Barbier additions of allylic and/or propargyl zinc reagents alternated with the hydrolysis of the unreacted imine function, followed by a cyclisation/dehydration sequence when a 1-amino-5-pentyne moiety was involved, all these steps being promoted by CeCl3.7 H2O.

引用

页码：158 / 160

页数：3

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