Generation of Human Oogonia From Induced Pluripotent Stem Cells In Vitro

被引：0

作者：

Yamashiro, Chika ^{[1
,2
]}

Sasaki, Kotaro ^{[1
,2
]}

Yabuta, Yukihiro ^{[1
,2
]}

Kojima, Yoji ^{[1
,2
,3
,4
]}

Nakamura, Tomonori ^{[1
,2
]}

Okamoto, Ikuhiro ^{[1
,2
]}

Yokobayashi, Shihori ^{[1
,2
,4
]}

Murase, Yusuke ^{[1
,2
]}

Ishikura, Yukiko ^{[1
,2
]}

Shirane, Kenjiro ^{[5
,6
,7
]}

Sasaki, Hiroyuki ^{[5
,6
,7
]}

Yamamoto, Takuya ^{[3
,4
,8
]}

Saitou, Mitinori ^{[1
,2
,3
,4
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Anat & Cell Biol, Kyoto, Japan

[2] Kyoto Univ, Exploratory Res Adv Technol ERATO, Japan Sci & Technol Agcy, Kyoto, Japan

[3] Kyoto Univ, Inst Integrated Cell Mat Sci, Kyoto, Japan

[4] Kyoto Univ, Ctr iPS Cell Res & Applicat, Kyoto, Japan

[5] Kyushu Univ, Div Epigen, Med Inst Bioregulat, Fukuoka, Fukuoka, Japan

[6] Kyushu Univ, Epigenome Network Res Ctr, Fukuoka, Fukuoka, Japan

[7] Kyushu Univ, Grad Sch Med Sci, Fukuoka, Fukuoka, Japan

[8] AMED, Agcy Med Res & Dev, Core Res Evolut Sci & Technol AMED CREST, Tokyo, Japan

来源：

OBSTETRICAL & GYNECOLOGICAL SURVEY | 2019年 / 74卷 / 03期

关键词：

D O I：

10.1097/OGX.0000000000000659

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

(Abstracted from Science 2018;362:356-360) Studies have shown that mouse pluripotent stem cells (PSCs) can be induced into primordial germ cell-like cells (hPGCLCs), which, following transplantation under appropriate conditions, can contribute to the development of gametes capable of developing into fertile offspring. Human in vitro gametogenesis from PSCs has long-reaching implications in reproductive medicine but has not yet been achieved.

引用

页码：158 / 159

页数：2

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