Generation of Human Oogonia From Induced Pluripotent Stem Cells In Vitro

被引：0
作者：
Yamashiro, Chika [1 ,2 ]
Sasaki, Kotaro [1 ,2 ]
Yabuta, Yukihiro [1 ,2 ]
Kojima, Yoji [1 ,2 ,3 ,4 ]
Nakamura, Tomonori [1 ,2 ]
Okamoto, Ikuhiro [1 ,2 ]
Yokobayashi, Shihori [1 ,2 ,4 ]
Murase, Yusuke [1 ,2 ]
Ishikura, Yukiko [1 ,2 ]
Shirane, Kenjiro [5 ,6 ,7 ]
Sasaki, Hiroyuki [5 ,6 ,7 ]
Yamamoto, Takuya [3 ,4 ,8 ]
Saitou, Mitinori [1 ,2 ,3 ,4 ]
机构：
[1] Kyoto Univ, Grad Sch Med, Dept Anat & Cell Biol, Kyoto, Japan
[2] Kyoto Univ, Exploratory Res Adv Technol ERATO, Japan Sci & Technol Agcy, Kyoto, Japan
[3] Kyoto Univ, Inst Integrated Cell Mat Sci, Kyoto, Japan
[4] Kyoto Univ, Ctr iPS Cell Res & Applicat, Kyoto, Japan
[5] Kyushu Univ, Div Epigen, Med Inst Bioregulat, Fukuoka, Fukuoka, Japan
[6] Kyushu Univ, Epigenome Network Res Ctr, Fukuoka, Fukuoka, Japan
[7] Kyushu Univ, Grad Sch Med Sci, Fukuoka, Fukuoka, Japan
[8] AMED, Agcy Med Res & Dev, Core Res Evolut Sci & Technol AMED CREST, Tokyo, Japan
来源：
OBSTETRICAL & GYNECOLOGICAL SURVEY | 2019年 / 74卷 / 03期
关键词：
D O I：
10.1097/OGX.0000000000000659
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
(Abstracted from Science 2018;362:356-360) Studies have shown that mouse pluripotent stem cells (PSCs) can be induced into primordial germ cell-like cells (hPGCLCs), which, following transplantation under appropriate conditions, can contribute to the development of gametes capable of developing into fertile offspring. Human in vitro gametogenesis from PSCs has long-reaching implications in reproductive medicine but has not yet been achieved.
引用
收藏
页码：158 / 159
页数：2
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