The Relationship of Wound Healing with Psoriasis and Multiple Sclerosis

被引：4
|
作者：
Morhenn, Vera B. [1 ]
机构：
[1] San Francisco VA Med Ctr, Dept Dermatol, 4150 Clement St, San Francisco, CA 94121 USA
来源：
ADVANCES IN WOUND CARE | 2018年 / 7卷 / 06期
关键词：
wound healing; psoriasis; multiple sclerosis; ENDOTHELIAL GROWTH-FACTOR; NMDA RECEPTOR; EXPRESSION; KERATINOCYTES; PATHOGENESIS; SYSTEM;
D O I：
10.1089/wound.2017.0773
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Significance: Better understanding of wound healing could lead to improved treatment(s) of multiple sclerosis (MS) and psoriasis (Pso). Recent Advances: New concepts in the events of wound healing, such as the roles of the innate and adaptive immune systems, have generated targets for treating these debilitating diseases. Innovation: That in MS and Pso defective wound healing is responsible for the diseases' progression has not been hypothesized to date. Conclusion: Impaired initiation of wound repair by oligodendrocyte precursor cells or oligodendrocytes may play a role in MS, and a lack of inhibition of the proliferative phase in wound healing may explain the pathophysiology involved in Pso.
引用
收藏
页码：185 / 188
页数：4
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