Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis

被引：34

作者：

Alam, Sarwar ^{[1
]}

Ali, Iqbal ^{[2
]}

Giri, K. Y. ^{[1
]}

Gokkulakrishnan, S. ^{[1
]}

Natu, Subodh S. ^{[2
]}

Faisal, Mohammad ^{[3
]}

Agarwal, Anshita ^{[4
]}

Sharma, Himanshu ^{[1
]}

机构：

[1] Inst Dent Sci, Dept Oral & Maxillofacial Surg, Bareilly 243006, Uttar Pradesh, India

[2] Career Post Grad Inst Dent Sci & Hosp, Dept Oral & Maxillofacial Surg, Lucknow, Uttar Pradesh, India

[3] Jamia Millia Islamia, Dept Oral & Maxillofacial Surg, Fac Dent, New Delhi 110025, India

[4] Vananchal Dent Coll & Hosp, Dept Oral Pathol, Garhwa, Jharkhand, India

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY | 2013年 / 116卷 / 06期

关键词：

SURGICAL-TREATMENT; MANAGEMENT;

D O I：

10.1016/j.oooo.2013.08.003

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Objective. Definitive therapy is not defined for the management of oral submucous fibrosis (OSMF). This study evaluated the efficacy of aloe vera gel as an adjuvant treatment of OSMF. Study Design. A double-blind, placebo-controlled, parallel-group randomized controlled trial was conducted on 60 subjects with OSMF divided into medicinal treatment (submucosal injection of hyaluronidase and dexamethasone, n = 30) and surgical treatment (n = 30) categories. Each category was randomly divided into groups A (with aloe vera, n = 15 per category) and B (without aloe vera, n = 15 per category). Follow-up assessment for various symptoms was performed, and results were analyzed using paired and unpaired Student t tests. Results. The group receiving aloe vera had a significant improvement in most symptoms of OSMF (P < .01) compared with the non-aloe vera group, in both the medicinal and surgical categories. Conclusions. Aloe vera gel was effective as an adjuvant in treatment of OSMF.

引用

页码：717 / 724

页数：8

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