Small bowel polyps and tumours: endoscopic detection and treatment by double-balloon enteroscopy

被引:41
作者
Fry, L. C. [1 ]
Neumann, H. [1 ]
Kuester, D. [2 ]
Kuhn, R. [3 ]
Bellutti, M. [1 ]
Malfertheiner, P. [1 ]
Monkemuller, K. [1 ]
机构
[1] Otto VonGuericke Univ Magdegurg, Dept Gastroenterol Hepatol & Infect Dis, D-39120 Magdeburg, Germany
[2] Otto VonGuericke Univ Magdegurg, Dept Pathol, D-39120 Magdeburg, Germany
[3] Otto VonGuericke Univ Magdegurg, Dept Surg, D-39120 Magdeburg, Germany
关键词
FAMILIAL ADENOMATOUS POLYPOSIS; PEUTZ-JEGHERS-SYNDROME; GASTROINTESTINAL POLYPOSIS; CAPSULE ENDOSCOPY; DIAGNOSTIC YIELD; COMPLICATIONS; DISEASE; CANCER; METAANALYSIS;
D O I
10.1111/j.1365-2036.2008.03864.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background Double-balloon enteroscopy has allowed us not only to inspect deeply the small bowel but also to carry out interventions for diseases of the small bowel. Aim To evaluate the utility of double-balloon enteroscopy for the diagnosis and therapy of these lesions. Methods All patients undergoing double-balloon enteroscopy for evaluation of small bowel polyps and tumours during a 3.75-year period at a university referral hospital were studied. The types of polyps and tumours as well as endoscopic technique of removal, surgery and complications were documented. Results The incidence of small bowel polyps and tumours in-patients undergoing DBE was 9.6%. A total of 40 double-balloon enteroscopy procedures were performed in 29 patients [13 female (44.8%), mean age 51 years, range 22-74]. The following lesions were found most frequently: adenomas in familial adenomatous polyposis syndrome, n = 8; hamartomas, n = 4 (Peutz-Jeghers and Cronkhite Canada syndromes), jejunal adenocarcinoma n = 5, neuroendocrine tumour n = 4 and others n = 6. Conclusions The incidence of small bowel tumours in those in-patients who were undergoing double-balloon enteroscopy was 10%. Double-balloon enteroscopy is useful for the diagnosis and treatment of small bowel polyps and tumours.
引用
收藏
页码:135 / 142
页数:8
相关论文
共 26 条
[1]  
Brosens LAA, 2007, CURR MOL MED, V7, P29
[2]   Familial adenomatous polyposis [J].
Galiatsatos, P ;
Foulkes, WD .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2006, 101 (02) :385-398
[3]   Very high risk of cancer in familial Peutz-Jeghers syndrome [J].
Giardiello, FM ;
Brensinger, JD ;
Tersmette, AC ;
Goodman, SN ;
Petersen, GM ;
Booker, SV ;
Cruz-Correa, M ;
Offerhaus, JA .
GASTROENTEROLOGY, 2000, 119 (06) :1447-1453
[4]   AGA technical review on hereditary colorectal cancer and genetic testing [J].
Giardiello, FM ;
Brensinger, JD ;
Petersen, GM .
GASTROENTEROLOGY, 2001, 121 (01) :198-213
[5]   Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy [J].
Goldstein, J. L. ;
Eisen, G. M. ;
Lewis, B. ;
Gralnek, I. M. ;
Aisenberg, J. ;
Bhadra, P. ;
Berger, M. F. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 25 (10) :1211-1222
[6]   Double-balloon enteroscopy: Indications, diagnostic yield, and complications in a series of 275 patients with suspected small-bowel disease [J].
Heine, GDN ;
Hadithi, M ;
Groenen, MJM ;
Kuipers, EJ ;
Jacobs, MAJM ;
Mulder, CJJ .
ENDOSCOPY, 2006, 38 (01) :42-48
[7]   Meta-analysis: capsule enteroscopy vs. conventional modalities in diagnosis of small bowel diseases [J].
Marmo, R ;
Rotondano, G ;
Piscopo, R ;
Bianco, MA ;
Cipolletta, L .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2005, 22 (07) :595-604
[8]   Push-and-pull enteroscopy using the double-balloon technique: Method of assessing depth of insertion and training of the enteroscopy technique using the erlangen endo-trainer [J].
May, A ;
Nachbar, L ;
Schneider, M ;
Neumann, M ;
Ell, C .
ENDOSCOPY, 2005, 37 (01) :66-70
[9]   Complications of double balloon enteroscopy:: a multicenter survey [J].
Mensink, P. B. F. ;
Haringsma, J. ;
Kucharzik, T. ;
Cellier, C. ;
Perez-Cuadrado, E. ;
Wonkemuller, K. ;
Gasbarrini, A. ;
Kaffes, A. J. ;
Nakamura, K. ;
Yen, H. H. ;
Yamamoto, H. .
ENDOSCOPY, 2007, 39 (07) :613-615
[10]   Small-bowel tumors [J].
Minardi, AJ ;
Zibari, GB ;
Aultman, DF ;
McMillan, RW ;
McDonald, JC .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 1998, 186 (06) :664-668