Analytical methods for human biomonitoring of pesticides. A review

被引:96
作者
Yusa, Vicent [1 ,2 ,3 ]
Millet, Maurice [4 ]
Coscolla, Clara [1 ,2 ]
Roca, Marta [1 ,2 ]
机构
[1] Fdn Promot Hlth & Biomed Res Valencian Reg, FISABIO Publ Hlth, Valencia 46020, Spain
[2] Publ Hlth Lab Valencia, Valencia, Spain
[3] Univ Valencia, Dept Analyt Chem, E-46003 Valencia, Spain
[4] Univ Strasbourg, CNRS, ICPEES, UMR 7515,Grop Physicochim Atmosphere, Strasbourg, France
关键词
Biomonitoring; Pesticides; Blood; Urine; Hair; TANDEM MASS-SPECTROMETRY; SOLID-PHASE EXTRACTION; PERSISTENT ORGANIC POLLUTANTS; OF-THE-ART; MULTI-RESIDUE METHOD; DRIED BLOOD SPOTS; HUMAN URINE; ORGANOPHOSPHATE PESTICIDES; SAMPLE PREPARATION; POLYCHLORINATED-BIPHENYLS;
D O I
10.1016/j.aca.2015.05.032
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Biomonitoring of both currently-used and banned-persistent pesticides is a very useful tool for assessing human exposure to these chemicals. In this review, we present current approaches and recent advances in the analytical methods for determining the biomarkers of exposure to pesticides in the most commonly used specimens, such as blood, urine, and breast milk, and in emerging non-invasive matrices such as hair and meconium. We critically discuss the main applications for sample treatment, and the instrumental techniques currently used to determine the most relevant pesticide biomarkers. We finally look at the future trends in this field. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:15 / 31
页数:17
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