Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review

被引:8
作者
Manwaring, Jotham [1 ]
Ahmadian, Amir [1 ]
Stapleton, Stacie [3 ]
Gonzalez-Gomez, Ignacio [4 ]
Rodriguez, Luis [1 ,2 ]
Carey, Carolyn [1 ,2 ]
Tuite, Gerald F. [1 ,2 ]
机构
[1] Univ S Florida, Morsani Sch Med, Dept Neurosurg & Brain Repair, Tampa, FL USA
[2] All Childrens Hosp Johns Hopkins Med, Inst Neurosci, St Petersburg, FL 33701 USA
[3] All Childrens Hosp Johns Hopkins Med, Dept Pediat Hematol Oncol, St Petersburg, FL 33701 USA
[4] All Childrens Hosp Johns Hopkins Med, Dept Pathol, St Petersburg, FL 33701 USA
关键词
Extra-axial tumors; Meningiomas; Microcystic; Pediatric brain tumor; INTRACRANIAL MENINGIOMAS; BRAIN EDEMA; CHILDREN; CHILDHOOD; FEATURES; MR;
D O I
10.1007/s00381-012-1991-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Microcystic meningioma (MM) is a World Health Organization grade I tumor that is rare in the pediatric population. Meningiomas account for approximately 2-4 % of all childhood central nervous system (CNS) tumors compared to approximately 20 % of all adult CNS tumors. The authors present one of the few confirmed cases of microcystic meningioma in a child and discuss the characteristic radiographic appearance and histological findings. We report the case of an 11-year-old boy who presented with first-time seizure and imaging consistent with brain tumor. There was significant vasogenic edema within the entire right hemisphere, disproportionate to the size of the falcine-based tumor. Histopathological analysis revealed the microcystic subtype of meningioma. We review the radiographic characteristics, histopathological findings, and reported pediatric cases of MM in conjunction with our case. MM has distinct radiographic characteristics (variable enhancement, lack of a dural tail, and disproportionate vasogenic edema) that can be misinterpreted in the pediatric population, suggesting a more aggressive tumor.
引用
收藏
页码:361 / 365
页数:5
相关论文
共 28 条
[1]   Stereotactic radiosurgery for benign meningiomas [J].
Bloch, Orin ;
Kaur, Gurvinder ;
Jian, Brian J. ;
Parsa, Andrew T. ;
Barani, Igor J. .
JOURNAL OF NEURO-ONCOLOGY, 2012, 107 (01) :13-20
[2]   Microcystic meningioma: Importance of obvious hypointensity on T1-weighted magnetic resonance images [J].
Chen, Chi-Jen ;
Tseng, Ying-Chi ;
Hsu, Hui-Ling ;
Jung, Shih-Ming .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2008, 32 (01) :130-134
[3]  
Cho Jun Hyung, 2003, [Journal of Korean Neurosurgical Society, 대한신경외과학회지], V34, P382
[4]  
Cuccurullo L, 2009, PATHOLOGICA, V101, P115
[5]   Stereotactic radiotherapy for intracranial meningioma [J].
Delannes, M. ;
Maire, J. -P. ;
Sabatier, J. ;
Thillays, F. .
CANCER RADIOTHERAPIE, 2012, 16 :S79-S89
[6]   WHO grade II and III meningiomas: a study of prognostic factors [J].
Durand, Anne ;
Labrousse, Francois ;
Jouvet, Anne ;
Bauchet, Luc ;
Kalamarides, Michel ;
Menei, Philippe ;
Deruty, Robert ;
Moreau, Jean Jacques ;
Fevre-Montange, Michelle ;
Guyotat, Jacques .
JOURNAL OF NEURO-ONCOLOGY, 2009, 95 (03) :367-375
[7]  
GLASIER CM, 1993, AM J NEURORADIOL, V14, P237
[8]   Perfusion MR imaging and 1H spectroscopy: Their role in the diagnosis of microcystic and lipomatous meningiomas [J].
Grand, S. ;
Pasquier, B. M. ;
Hoffmann, D. M. ;
Krainik, A. ;
Ashraf, A. ;
Tropres, I. M. ;
Dillworth, K. ;
Le Bas, J. F. .
JOURNAL OF NEURORADIOLOGY, 2010, 37 (03) :185-188
[9]   Meningiomas in children [J].
Greene, Stephanie ;
Nair, Nathan ;
Ojemann, Jeffrey G. ;
Ellenbogen, Richard G. ;
Avellino, Anthony M. .
PEDIATRIC NEUROSURGERY, 2008, 44 (01) :9-13
[10]   Childhood meningioma: unusual location, atypical radiological findings, and favorable treatment outcome [J].
Im, SH ;
Wang, KC ;
Kim, SK ;
Oh, CW ;
Kim, DG ;
Hong, SK ;
Kim, NR ;
Chi, JG ;
Cho, BK .
CHILDS NERVOUS SYSTEM, 2001, 17 (11) :656-662