DOPAMINERGIC ACTIVITY COINCIDES WITH STIMULUS DETECTION BY THE FRONTAL LOBE

被引：16

作者：

de Lafuente, V. ^{[1
]}

Romo, R. ^{[2
,3
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Neurobiol, Queretaro 76230, Qro, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Fisiol Celular Neurociencias, Mexico City 04510, DF, Mexico

[3] Colegio Nacl, Mexico City 06020, DF, Mexico

来源：

NEUROSCIENCE | 2012年 / 218卷

关键词：

dopamine; perception; reward; detection; somatosensory; decisions; SUBJECTIVE SENSORY EXPERIENCE; SOMATOSENSORY CORTEX; MONKEY MIDBRAIN; SHORT-LATENCY; NEURONS; RESPONSES; CONTINGENCIES; PRIMATE; PATHWAY; SIGNAL;

D O I：

10.1016/j.neuroscience.2012.05.026

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

For midbrain dopamine (DA) neurons to respond to sensory events, the presence of a stimulus must first be detected. Where is the signal that activates DA neurons coming from? Here we show that DA responses to a vibrotactile stimulus lag significantly behind those of the primary somatosensory cortex, but they arise with a latency that closely matches the onset of premotor neurons known to encode perceptual decisions. In agreement with previous findings, these data suggest that sensory evoked DA activity does not signal a stimulus physical presence but arises from the output of a perceptual decision. (C) 2012 IBRO. Published by Elsevier Ltd. All rights reserved.

引用

页码：181 / 184

页数：4

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