WOUND HEALING ACTIVITY OF AQUEOUS EXTRACTS OF LEAVES AND ROOTS OF COLEUS AROMATICUS IN RATS

被引：0
|
作者：
Jain, Anand K. [1 ]
Dixit, Ashish [2 ]
Mehta, Swaroop C. [1 ]
机构：
[1] GR Med Coll, Dept Pharmacol, Gwalior 474009, MP, India
[2] RNS Coll Pharmaceut Sci & Res, Gwalior, MP, India
来源：
ACTA POLONIAE PHARMACEUTICA | 2012年 / 69卷 / 06期
关键词：
wound healing; tensile strength; hydroxyproline content; Coleus aromaticus; TRIDAX-PROCUMBENS;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Present study was aimed to evaluate the wound healing activity of aqueous extract of leaves and roots of Coleus aromaticus using excisional wound model in albino rats. The aqueous extracts were prepared using maceration method and were applied as 5% and 10% ointment. The wound healing activity of these extracts was compared with a standard drug povidone-iodine ointment. The healing tissue was also tested for tensile strength, hydroxyproline content and protein content. The histopathological examination of healing tissue was also performed. Ten percent ointment of aqueous extract of root showed complete epithelization after 12 days (p < 0.01) and 5% ointment of leaf extract showed complete healing after 16 days (p < 0.01).
引用
收藏
页码：1119 / 1123
页数：5
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