Cytomegalovirus (CMV) resistance to antivirals

被引：0
作者：
Drew, WL [1 ]
Paya, CV
Emery, V
机构：
[1] Univ Calif San Francisco, Mt Zion Med Ctr, Dept Lab Med, San Francisco, CA 94120 USA
[2] Mayo Clin, Div Infect Dis, Rochester, MN USA
[3] Mayo Clin, Transplant Ctr, Rochester, MN USA
[4] UCL Royal Free & Univ Coll Med Sch, Dept Virol, London, England
来源：
AMERICAN JOURNAL OF TRANSPLANTATION | 2001年 / 1卷 / 04期
关键词：
antiviral resistance; CMV;
D O I：
暂无
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
This article reviews the biology of cytomegalovirus (CMV), the approved antiviral therapies, and mechanisms of resistance to these drugs. The rates of resistance development in clinical trials are presented, as are the assays for testing susceptibility by phenotypic and genotypic methods. Factors that favor the development of clinical and in vitro antiviral resistance are discussed. Finally, approaches to altering antiviral therapy as resistance develops are outlined.
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页码：307 / 312
页数：6
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