The wide array of peripheral arterial diseases (PAD) includes stenosis of the subclavian artery. Estimated around 2percent of the total population is thought to have subclavian artery, which is the incidence of subclavian artery stenosis. Individualsmore than 70 years of age have a 15% prevalence of PAD. Five percent of patients will have critical limb ischemia out of this group and roughly a quarter of them will need revascularization. Left subclavian artery stenosis affects almost fifty percent of patients with documented peripheral arterial disease, accounting for 30% of all cases. Due to the sluggish course of the disease, a large population of individuals is asymptomatic. Once the vessel diameter has shrunk by 50% at the luminal end, symptoms frequently start to show. The disease is most prevalent in the sixth to seventh decade of life, with symptoms ranging from central nervous system to the circulatory system including pain, swelling, numbness, ischemic changes and vertigo to name a few. The primary method for diagnosing and treating sympathetically sustained pain disorders involving the upper extremities, such as complicated regional pain syndrome, is stellate ganglion block, a minimally invasive operation (CRPS). The stellate ganglion block can be a great treatment modality in multiple neuropathic pain disorders, including ischemic neuropathies, painfulviral infections such as herpes zoster (shingles), early PHN and post-radiation neuritis, where it has been found effective in pain relief.