Sex- and gender-differences in chronic long-term complications of type 1 and type 2 diabetes mellitus in Italy

被引:7
作者
Russo, G. T. [1 ,7 ]
Manicardi, V. [2 ]
Rossi, M. C. [3 ]
Orsi, E. [4 ]
Solini, A. [5 ,6 ]
机构
[1] Univ Messina, Dept Clin & Expt Med, Messina, Italy
[2] AMD Fdn, Reggio Emilia, Italy
[3] CORESEARCH Ctr Outcomes Res & Clin Epidemiol, Pescara, Italy
[4] IRCCS Fdn Ca Grande Osped Maggiore, Milan, Italy
[5] Univ Pisa, Dept Surg Med Mol & Crit Area Pathol, Pisa, Italy
[6] Univ Pisa, Dept Surg Med Mol & Crit Area Pathol, Via Roma 67, I-56126 Pisa, Italy
[7] Univ Messina, Policlin Univ G Martino, Dept Clin & Expt Med, Via C Valeria, I-98123 Messina, Italy
关键词
Gender; Sex; Complications; Type; 2; diabetes; 1; Italy; CARDIOVASCULAR RISK-FACTORS; CORONARY-HEART-DISEASE; LEFT-VENTRICULAR DYSFUNCTION; CAUSE-SPECIFIC MORTALITY; FATTY LIVER-DISEASE; VASCULAR COMPLICATIONS; RENAL-INSUFFICIENCY; GLYCEMIC CONTROL; KIDNEY-DISEASE; 64; COHORTS;
D O I
10.1016/j.numecd.2022.08.011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: This review summarizes the contribution of Italian diabetologists devoted to a better understanding of the complex relationship linking sex/gender and long-term complications of type 1 (T1DM) and type 2 diabetes (T2DM) over the last fifteen years.Data synthesis: Microvascular and macrovascular complications of diabetes show sex- and gender-related differences, involving pathophysiological mechanisms, epidemiological features and clinical presentation, due to the interaction between biological and psychosocial factors. These differences greatly impact on the progression of diabetes and its long-term complications, especially in the cardiovascular, renal and liver districts.Conclusion: A better knowledge of such sex- and gender-related characteristics is required for a more precise patient phenotypization, and for the choice of a personalized antihyperglycemic treatment. Despite such mounting evidence, current diabetes clinical guidelines do not as yet adequately consider sex/gender differences.(c) 2022 Published by Elsevier B.V. on behalf of The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University.
引用
收藏
页码:2297 / 2309
页数:13
相关论文
共 140 条
[61]   Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus [J].
Lovshin, Julie A. ;
Skrtic, Marko ;
Bjornstad, Petter ;
Moineddin, Rahim ;
Daneman, Denis ;
Dunger, David ;
Reich, Heather N. ;
Mahmud, Farid ;
Scholey, James ;
Cherney, David Z., I ;
Sochetts, Etienne .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2018, 314 (04) :F667-F674
[62]   Update on Management of Cardiovascular Diseases in Women [J].
Luca, Fabiana ;
Abrignani, Maurizio Giuseppe ;
Parrini, Iris ;
Di Fusco, Stefania Angela ;
Giubilato, Simona ;
Rao, Carmelo Massimiliano ;
Piccioni, Laura ;
Cipolletta, Laura ;
Passaretti, Bruno ;
Giallauria, Francesco ;
Leone, Angelo ;
Francese, Giuseppina Maura ;
Riccio, Carmine ;
Gelsomino, Sandro ;
Colivicchi, Furio ;
Gulizia, Michele Massimo .
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (05)
[63]   Nonalbuminuric renal insufficiency in type 2 diabetes [J].
MacIsaac, R ;
Tsalamandris, C ;
Panagiotopoulos, S ;
Smith, T ;
McNeil, K ;
Jerums, G .
DIABETES CARE, 2004, 27 (01) :195-200
[64]   Left ventricular diastolicdysfunction in normotensive postmenopausal women with type 2 diabetes mellitus [J].
Maiello, Maria ;
Zito, Annapaola ;
Cecere, Annagrazia ;
Ciccone, Marco Matteo ;
Palmiero, Pasquale .
CARDIOLOGY JOURNAL, 2017, 24 (01) :51-56
[65]  
Manicardi V., 2016, ITALIAN J GENDER SPE, V2, P60, DOI DOI 10.1723/2446.25646
[66]   Gender-Disparitiesin Adults with Type 1 Diabetes: More Than a Quality of Care Issue. A Cross-Sectional Observational Study from the AMD Annals Initiative [J].
Manicardi, Valeria ;
Russo, Giuseppina ;
Napoli, Angela ;
Torlone, Elisabetta ;
Li Volsi, Patrizia ;
Giorda, Carlo Bruno ;
Musacchio, Nicoletta ;
Nicolucci, Antonio ;
Suraci, Concetta ;
Lucisano, Giuseppe ;
Rossi, Maria Chiara .
PLOS ONE, 2016, 11 (10)
[67]   Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis [J].
Mantovani, Alessandro ;
Petracca, Graziana ;
Beatrice, Giorgia ;
Csermely, Alessandro ;
Lonardo, Amedeo ;
Schattenberg, Jorn M. ;
Tilg, Herbert ;
Byrne, Christopher D. ;
Targher, Giovanni .
GUT, 2022, 71 (01) :156-162
[68]   Cardiovascular prevention in women: a narrative review from the Italian Society of Cardiology working groups on 'Cardiovascular Prevention, Hypertension and peripheral circulation' and on 'Women Disease' [J].
Mattioli, Anna Vittoria ;
Sciomer, Susanna ;
Moscucci, Federica ;
Maiello, Maria ;
Cugusi, Lucia ;
Gallina, Sabina ;
Dei Cas, Alessandra ;
Lombardi, Carolina ;
Pengo, Martino ;
Parati, Gianfranco ;
Barilla, Francesco ;
Ciccone, Marco Matteo ;
Palmiero, Pasquale ;
Mercuro, Giuseppe ;
Maffei, Silvia .
JOURNAL OF CARDIOVASCULAR MEDICINE, 2019, 20 (09) :575-583
[69]  
Mauvais-Jarvis F, 2020, LANCET, V396, P565, DOI 10.1016/S0140-6736(20)31561-0
[70]   Gender differences in glucose homeostasis and diabetes [J].
Mauvais-Jarvis, Franck .
PHYSIOLOGY & BEHAVIOR, 2018, 187 :20-23