Survival Outcomes of Patients with Primary Breast Cancer Following Primary Ovarian Cancer

被引:5
作者
Zhang, Wei [1 ]
Zhang, Wenque [1 ]
Lin, Zhihong [1 ]
Wang, Fang [1 ]
Li, Miaojie [1 ]
Zhu, Libo [2 ]
Yu, Yixian [3 ]
Gao, Yutao [3 ]
机构
[1] Kunming Med Univ, Affiliated Hosp 6, Peoples Hosp Yuxi City, Dept Gynaecol, Yuxi, Yunnan, Peoples R China
[2] Dali Bai Autonomous Prefecture Peoples Hosp, Dept Gastroenterol, Dali, Yunnan, Peoples R China
[3] Kunming Med Univ, Affiliated Hosp 1, Dept Gynecol, Kunming, Yunnan, Peoples R China
来源
MEDICAL SCIENCE MONITOR | 2019年 / 25卷
关键词
Ovarian Neoplasms; SEER Program; Triple Negative Breast Neoplasms; MUTATION CARRIERS; RISK; WOMEN; BRCA1; STATISTICS; PATTERNS;
D O I
10.12659/MSM.914163
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Patients with primary breast cancer following primary ovarian cancer do not comprise a large clinical entity, and reports of the survival outcomes of this cohort are rare. The purpose of this retrospective population-based research was to investigate the survival outcomes of patients with primary breast cancer after primary ovarian cancer. Material/Methods: A cohort of patients diagnosed with primary breast cancer following primary ovarian cancer between 1973 and 2014 was drawn from the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) database. Cox proportional hazards survival regression analysis and Kaplan-Meier were applied to calculate overall survival (OS), cancer-specific survival (CSS), and independent predictors of CSS. Results: A total of 1455 patients with primary breast cancer following primary ovarian cancer were identified. The 5-year and 10-year OS rates for the entire cohort were 81.7% and 67.4%, respectively. The 5-year and 10-year CSS rates were 84.2% and 74.3% for ovarian cancer, and 76.0% and 67.8% for breast cancer, respectively. Multivariate analysis revealed that independent predictors of ovarian cancer CSS include age, cancer stage, diagnosis time, and histological subtype. Conclusions: Patients diagnosed with breast cancer following ovarian cancer have better survival rates. Patients age, ovarian cancer stage, ovarian cancer histological type, and time of diagnose affect the survival rate.
引用
收藏
页码:3869 / 3879
页数:11
相关论文
共 50 条
[41]   Multiple second primary tumors in a woman following breast cancer [J].
Kantzou, I. ;
Sarris, G. ;
Kalinoglou, N. ;
Karagiannis, V. ;
Hrisanthou, K. .
JOURNAL OF BUON, 2009, 14 (03) :531-532
[42]   Impact of a national cancer awareness campaign in primary breast cancer patients [J].
Barrault, M. ;
Michel, G. ;
Cousson-Gelie, F. .
ANNALES MEDICO-PSYCHOLOGIQUES, 2010, 168 (06) :466-470
[43]   Survival for endometrial cancer as a second primary malignancy [J].
Medina, Heidy N. ;
Schlumbrecht, Matthew P. ;
Penedo, Frank J. ;
Pinheiro, Paulo S. .
CANCER MEDICINE, 2022, 11 (06) :1490-1501
[44]   Development of second primary cancer in Korean breast cancer survivors [J].
Jung, Hong Kyu ;
Park, Suyeon ;
Kim, Nam Won ;
Lee, Jong Eun ;
Kim', Zisun ;
Han, Sun Wook ;
Hur, Sung Mo ;
Kim, Sung Young ;
Lim, Cheol Wan ;
Lee, Min Hyuk ;
Lee, Jihyoun .
ANNALS OF SURGICAL TREATMENT AND RESEARCH, 2017, 93 (06) :287-292
[45]   The contribution of second primary cancers to the mortality of patients with a first primary breast cancer [J].
Goncalves, Elisabete ;
Fontes, Filipa ;
Rodrigues, Jessica Rocha ;
Calisto, Rita ;
Bento, Maria Jose ;
Lunet, Nuno ;
Morais, Samantha .
BREAST CANCER RESEARCH AND TREATMENT, 2024, 207 (02) :323-330
[46]   Methods of communicating a primary diagnosis of breast cancer to patients [J].
Lockhart, K. ;
Dosser, I ;
Cruickshank, S. ;
Kennedy, C. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2007, (03)
[47]   Second primary cancers in breast cancer patients in Slovenia [J].
N. Volk ;
V. Pompe-Kirn .
Cancer Causes & Control, 1997, 8 :764-770
[48]   Mammographic density and prognosis in primary breast cancer patients [J].
Heindl, Felix ;
Fasching, Peter A. ;
Hein, Alexander ;
Hack, Carolin C. ;
Heusinger, Katharina ;
Gass, Paul ;
Poeschke, Patrik ;
Stuebs, Frederik A. ;
Schulz-Wendtland, Rudiger ;
Hartmann, Arndt ;
Erber, Ramona ;
Beckmann, Matthias W. ;
Meyer, Julia ;
Haeberle, Lothar ;
Jud, Sebastian M. ;
Emons, Julius .
BREAST, 2021, 59 :51-57
[49]   Second primary cancers in breast cancer patients in Slovenia [J].
Volk, N ;
PompeKirn, V .
CANCER CAUSES & CONTROL, 1997, 8 (05) :764-770
[50]   Diagnosis of Primary Colorectal Carcinoma with Primary Breast Cancer: Associations or Connections? [J].
Weissman, Simcha ;
Sebrow, Jefferey ;
Gonzalez, Hector H. ;
Weingarten, Michael J. ;
Rosenblatt, Samuel ;
Mehta, Tej, I ;
Thaker, Rishi ;
Krzyzak, Michael ;
Saleem, Saad .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2019, 11 (03)