Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma

被引：12

作者：

Gogarty, Darragh S. ^{[1
,9
]}

Lennon, Paul ^{[2
]}

Deady, Sandra ^{[3
]}

O'Sullivan, J. Barry ^{[4
]}

McArdle, Orla ^{[5
]}

Leader, Mary ^{[6
]}

Sheahan, Patrick ^{[7
]}

O'Neill, James Paul ^{[8
]}

机构：

[1] St Vincents Univ Hosp, Anaesthesia, Dublin 4, Ireland

[2] Royal Coll Surgeons Ireland, Dept Otolaryngol Head & Neck Surg, 123 St Stephens Green, Dublin 2, Ireland

[3] Natl Canc Registry Ireland, Bldg 6800,Cork Airport Business Pk,Kinsale Rd, Cork, Ireland

[4] Beaumont Hosp, Beaumont Rd, Dublin 9, Ireland

[5] Beaumont Hosp, St Lukes Oncol Network, Beaumont Rd, Dublin 9, Ireland

[6] Royal Coll Surgeons Ireland, Dept Pathol, 123 St Stephens, Dublin 2, Ireland

[7] South Infirm Victoria Univ Hosp, Cork, Ireland

[8] Royal Coll Surgeons Ireland, Dept Otolaryngol Head & Neck Surg, 123 St Stephens Green, Dublin 2, Ireland

[9] Beaumont Hosp, RCSI Otolaryngol Head & Neck Surg, RCSI Educ & Res Ctr, Dublin 9, Ireland

来源：

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 2017年 / 274卷 / 02期

关键词：

Node negative; Oral cavity; Adult; Survival; Radiotherapy; ELECTIVE NECK DISSECTION; THERAPEUTIC NECK; PRIMARY SURGERY; PRIMARY SITE; N0; NECK; CANCER; SURVIVAL; TONGUE; RADIOTHERAPY; HEAD;

D O I：

10.1007/s00405-016-4267-z

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

This study aims to determine the survival impact of patient characteristics and treatment options associated with the early stage oral cavity squamous cell carcinoma, OCSCC. The methods are analysis of Irish cancer database examining T1/2, N0, and M0 cases of OCSCC from 1997 to 2007 inclusive. In total, 397 cases were identified. Anterolateral tongue accounted for 52.9 % of cases. Increased age at diagnosis and smoking are independent prognostic survival indicators associated with poorer outcomes. Surgery as the initial intervention was associated with significantly better survival outcomes, while surgery and adjuvant radiotherapy significantly worse outcomes. Surgical intervention is recommended as the first-line treatment in the early stage OCSCC in combination with elective neck dissection.

引用

页码：953 / 960

页数：8

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