Antiinflammatory activity of rotenoids from Clitoria fairchildiana

被引：7

作者：

da Silva, BP ^{[1
]}

Parente, JP ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Ctr Ciencias Saude, BR-21944970 Janeiro, Brazil

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷

关键词：

Clitoria fairchildiana; structure activity; rotenoids; capillary permeability; antiinflammatory;

D O I：

10.1002/ptr.807

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five structurally related rotenoids were isolated from the roots of Clitoria fairchildiana. The antiinflammatory activity was investigated using a capillary permeability assay. The protective effect was measured as the inhibition in vascular permeability produced by acetic acid in the peritoneal cavity. The results suggest that for maximum activity the maintenance of the B/C ring junction integrity is important. These findings support the traditional use of Clitoria species extracts in the treatment of inflammatory conditions. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：S87 / S88

页数：2

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