Immunohistochemical and electrophysiological demonstration of substance P in human vestibular ganglion cells

被引：6
|
作者：
Felix, H
Schickinger, B
Felix, D
机构：
[1] UNIV VIENNA,ENT DEPT,VIENNA,AUSTRIA
[2] UNIV BERN,DIV NEUROBIOL,CH-3012 BERN,SWITZERLAND
来源：
ACTA OTO-LARYNGOLOGICA | 1996年 / 116卷 / 02期
关键词：
substance P; immunohistochemistry; electrophysiology; human; vestibular ganglion;
D O I：
10.3109/00016489609137839
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
This study was performed in order to determine the immunohistochemical expression and distribution pattern as well as the electrophysiological actions of substance P in human vestibular ganglion cells. Substance P-like immunostaining was mainly found in the cytoplasm of small vestibular ganglion cells. In contrast, nerve fibers were not labelled. Using intracellular recording techniques, substance P produced a slow depolarization of membrane potentials accompanied by an increase in membrane resistance. Furthermore, an enhanced firing response to depolarization occurred.
引用
收藏
页码：273 / 276
页数：4
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