Idiopathic CD4 Lymphocytopenia (HIV-Negative AIDS): Case Report and Literature Review

被引：0

作者：

Aksoy, Firdevs ^{[1
]}

Aydin, Murat ^{[1
]}

Yilmaz, Gurdal ^{[1
]}

Guvercin, Ali Riza ^{[2
]}

Eyuboglu, Ilker ^{[3
]}

Sari, Ahmet ^{[3
]}

Bayramoglu, Gulcin ^{[4
]}

Koksal, Iftihar ^{[1
]}

机构：

[1] Karadeniz Tech Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Trabzon, Turkey

[2] Karadeniz Tech Univ, Dept Neurosurg, Fac Med, Trabzon, Turkey

[3] Karadeniz Tech Univ, Dept Radiol, Fac Med, Trabzon, Turkey

[4] Karadeniz Tech Univ, Dept Med Microbiol, Fac Med, Trabzon, Turkey

来源：

MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS | 2019年 / 8卷

关键词：

T-lymphocytopenia; idiopathic CD4-positive; rare diseases; Nocardia; nocardiosis; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; T-CELL LYMPHOCYTOPENIA; PATIENT; NOCARDIOSIS; MENINGITIS; RETINITIS; INFECTION; SECONDARY;

D O I：

10.4274/mjima.galenos.2019.2019.24

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Idiopathic CD4 lymphocytopenia (ICL), also known as non-HIV AIDS, is a rare disease characterized by opportunistic infections, malignancies, and autoimmune diseases. Idiopathic CD4 lymphocytopenia is defined as CD4+ T-lymphocyte level below 300/mm(3) in at least two measurements or less than 20% of total lymphocytes, which cannot be explained by any other condition, including HIV infection. Nocardia spp. are opportunistic microorganisms that is a frequent cause of infection in immunocompromised individuals. In this paper, we report a 50-year-old patient with ICL and intracranial brain abscess due to Nocardia farcinica and review th literature for related articles published between April 2012 and December 2018. These data suggest that there may be an underlying immunosuppression in adult patients who have infections that are recurrent, refractory, and caused by opportunistic pathogens.

引用

页数：8

共 65 条

[1] Nocardia Brain Abscess and CD4(+) Lymphocytopenia in a Previously Healthy Individual
Adjamian, Norair
Kikam, Adeline
Wessell, Kathryn Ruda
Casselman, Jason
Toller-Artis, Erin
Olasokan, Olapeju
Hostoffer, Robert W.
[J]. CASE REPORTS IN IMMUNOLOGY, 2015, 2015
[2] Progressive multifocal leukoencephalopathy in idiopathic CD4+lymphocytopenia
Aghoram, Rajeswari
Narayan, Sunil K.
[J]. JOURNAL OF NEUROVIROLOGY, 2018, 24 (04) : 526 - 528
[3] Ahmad Dina S, 2013, Avicenna J Med, V3, P37, DOI 10.4103/2231-0770.114121
[4] Treatment of Progressive Multifocal Leukoencephalopathy With Interleukin 7
Alstadhaug, Karl B.
Croughs, Therese
Henriksen, Stian
Leboeuf, Celine
Sereti, Irini
Hirsch, Hans H.
Rinaldo, Christine Hanssen
[J]. JAMA NEUROLOGY, 2014, 71 (08) : 1030 - 1035
[5] Nocardiosis: Updated Clinical Review and Experience at a Tertiary Center
Ambrosioni, J.
Lew, D.
Garbino, J.
[J]. INFECTION, 2010, 38 (02) : 89 - 97
[6] Nocardiosis of the Central Nervous System Experience From a General Hospital and Review of 84 Cases From the Literature
Anagnostou, Theodora
Arvanitis, Marios
Kourkoumpetis, Themistoklis K.
Desalermos, Athanasios
Carneiro, Herman A.
Mylonakis, Eleftherios
[J]. MEDICINE, 2014, 93 (01) : 19 - 32
[7] Anderson Michael, 2012, Pneumonol Alergol Pol, V80, P565
[8] Progressive Multifocal Leukoencephalopathy Localized in the Cerebellum and Brainstem Associated with Idiopathic CD4+ T Lymphocytopenia
Aotsuka, Yuya
Uzawa, Akiyuki
Nishimura, Kazutaka
Kojima, Kazuho
Yamaguchi, Mika
Makino, Takahiro
Nakamichi, Kazuo
Saijo, Masayuki
Kuwabara, Satoshi
[J]. INTERNAL MEDICINE, 2016, 55 (12) : 1645 - 1647
[9] Aydin M, 2015, TURK MIKROBIYOL CEM, V45, P188
[10] Suppressed withouta Cause: A Case of Idiopathic Immune Deficiency
Ayub, Muhammad Talha
Jafar, Munnam S.
Khalid, Muhammad
Baig, Muhammad A.
Mba, Benjamin
[J]. CUREUS, 2018, 10 (01):

← 1 2 3 4 5 6 7 →