Permeability of the blood-brain barrier in newborn rats with induced hyperthermic convulsions

被引：0
作者：
Gurina, OI
Ryabukhin, IA
Anin, AN
Antonova, OM
Degtyarev, DN
Rogatkin, SO
Volodin, NN
Chekhonin, VP
机构：
[1] VP SERBSKII STATE RES CTR SOCIAL & FORENS PSYCHIA,LAB IMMUNOCHEM,MOSCOW,RUSSIA
[2] RUSSIAN STATE MED UNIV,DEPT POSTGRAD EDUC,DEPT NEONATOL,MOSCOW 117437,RUSSIA
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 123卷 / 02期
关键词：
blood-brain barrier; glial fibrillary acidic protein; dexason; infrared radiation; enzyme-linked immunosorbent assay;
D O I：
10.1007/BF02766430
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The permeability of the blood-brain barrier in the brain-blood direction is examined in newborn rats with hyperthermic convulsions induced by exposure to infrared radiation. Impaired permeability of this barrier due to convulsions is characterized by increased serum concentration of glial fibrillary acidic protein. Dexason lowers the protein level, which confirms its stabilizing effect on the blood-brain barrier structure. The advantage of early dexason administration is shown.
引用
收藏
页码：123 / 125
页数：3
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