Seroprevalence of past dengue virus infection among children and adolescents in Singapore

被引：8

作者：

Ang, Li Wei ^{[1
]}

Cutter, Jeffery ^{[2
]}

James, Lyn ^{[1
]}

Goh, Kee Tai ^{[2
,3
]}

机构：

[1] Minist Hlth, Epidemiol & Dis Control Div, Singapore 169854, Singapore

[2] Minist Hlth, Communicable Dis Div, Singapore 169854, Singapore

[3] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore

来源：

JOURNAL OF MEDICAL VIROLOGY | 2015年 / 87卷 / 12期

关键词：

dengue; epidemics; pediatric; seroprevalence; EPIDEMIOLOGY; SEROEPIDEMIOLOGY; ANTIBODIES;

D O I：

10.1002/jmv.24287

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We conducted a pediatric seroprevalence study of dengue virus (DENV) infection in Singapore, a dengue endemic city-state. Residual sera from 1,200 Singapore residents aged 1-17 years seen in two hospitals between 2008 and 2010 were tested for anti-DENV IgG antibodies. The overall seroprevalence was 10.4% (95%CI: 8.7-12.1%). There had been a marked decline in seroprevalence in the 15-19-year age group over the last three decades, while the prevalence in the 1-5-year olds (12.6%) was significantly higher than that of the 1996-1997 pediatric survey (0.8%). The overall dengue seroprevalence in children and adolescents remained low. J. Med. Virol. 87:2159-2162, 2015. (c) 2015 Wiley Periodicals, Inc.

引用

页码：2159 / 2162

页数：4

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